Teaching Staff

2012

Previous Positions

Research Areas

Selected Publications / All Publications

Uluslararası hakemli dergilerde (SCI) yayımlanan makaleler :

1. ÖZDEMİR SAMET, ÜNER BURCU, KARAKÜÇÜK ALPTUĞ EREN, ÇELİK BURAK, SÜMER ENGİN, TAŞ ÇETİN (2023). Nanoemulsions as a Promising Carrier for Topical Delivery of Etodolac: Formulation Development and Characterization, Pharmaceutics 15 (10), 2510.

2. ŞİMŞEKLİ ÖYKÜ, BİLİNMİŞ İRFAN, ÇELİK SÜMEYYE, ARIK GİZEM, BABA ABDULLAH YÜCEL, KARAKÜÇÜK ALPTUĞ EREN, (2023). Advancing Biofilm Management through Nanoformulation Strategies: A Review of Dosage Forms and Administration Routes, Journal of Drug Targeting, 1-64.

3. GÜLBAĞ PINAR SILA, OKTAY AYŞE NUR, KARAKÜÇÜK ALPTUĞ EREN, ÇELEBİ FATMA NEVİN (2023). Formulation Strategies of Nanosuspensions for Various Administration Routes. PHARMACEUTICS, 15(5), 1520, DOI: 10.3390/pharmaceutics15051520.

4. KARAKÜÇÜK ALPTUG EREN, CANPINAR HANDE, ÇELEBI FATMA NEVIN (2022). Ritonavir nanosuspensions prepared by microfluidization with enhanced solubility and desirable immunological properties. PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY, 27(10), 1027-1037, https://doi.org/10.1080/10837450.2022.2145309.

5. ÖZDEMİR SAMET, KARAKÜÇÜK ALPTUĞ, ÇAKIRLI EGEMEN, SÜRÜCÜ BİLGE, ÜNER BURCU, BARAK TİMUR HAKAN, BARDAKCI HİLAL (2022). Development and Characterization of Viburnum opulus L. Extract-Loaded Orodispersible Films: Potential Route of Administration for Phytochemicals. JOURNAL OF PHARMACEUTICAL INNOVATION, https://doi.org/10.1007/s12247-022-09627-z.

6. KARAKUCUK ALPTUG, TORT SERDAR, HAN SEVTAP, OKTAY AYSE NUR, CELEBI NEVIN (2021). Etodolac nanosuspension based gel for enhanced dermal delivery: in vitro and in vivo evaluation. JOURNAL OF MICROENCAPSULATION, 38(4), 218-232., Doi: 10.1080/02652048.2021.1895344.

7. KARAKÜÇÜK ALPTUG EREN,ÇELEBI FATMA NEVIN (2020). Investigation of formulation and process parameters of wet media milling to develop etodolac nanosuspensions. PHARMACEUTICAL RESEARCH, 37(111), 1-18., Doi: 10.1007/s11095-020-02815-x

8. TASHAN EMINE,KARAKÜÇÜK ALPTUG EREN,ÇELEBI FATMA NEVIN (2020). Development of Nanocrystal Ziprasidone Orally Disintegrating Tablets: Optimization by Using Design of Experiment and In Vitro Evaluation. AAPS PHARMSCITECH, 21, 115, Doi:10.1208/s12249-020-01653-9

9. OKTAY AYSE NUR,ILBASMIS TAMER SIBEL,KARAKÜÇÜK ALPTUG EREN,ÇELEBI FATMA NEVIN (2020). Screening of stabilizing agents to optimize flurbiprofen nanosuspensions using experimental design. Journal of Drug Delivery Science and Technology, 57, 101690, Doi:
10.1016/j.jddst.2020.101690.

10. KARAKÜÇÜK ALPTUG EREN,TORT SERDAR (2020). Preparation, characterization and antimicrobial activity evaluation of electrospun PCL nanofiber composites of resveratrol nanocrystals. Pharmaceutical Development and Technology, 25(10), 1216-1225., Doi:10.1080/10837450.2020.1805761.

11. TASHAN EMINE,KARAKÜÇÜK ALPTUG EREN,ÇELEBI FATMA NEVIN (2019). Optimization and in vitro evaluation of ziprasidone nanosuspensions produced by a top-down approach. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 52, 37-45., Doi:10.1016/j.jddst.2019.04.024.

12. KARAKÜÇÜK ALPTUG EREN,TEKSIN ZEYNEP SAFAK,EROGLU HAKAN,ÇELEBI FATMA NEVIN (2019). Evaluation of improved oral bioavailability of ritonavir nanosuspension. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 131, 153-158., Doi:10.1016/j.ejps.2019.02.028.

13. OKTAY AYSE NUR,KARAKÜÇÜK ALPTUG EREN,ILBASMIS TAMER SIBEL,ÇELEBI FATMA NEVIN (2018). Dermal flurbiprofen nanosuspensions: Optimization with design of experiment approach and in vitro evaluation. European Journal of Pharmaceutical Sciences, 122, 254-263., Doi: 10.1016/j.ejps.2018.07.009.

14. Aziz Zarith Asyikin,Ahmad Akil,Setapar Siti Hamidah,KARAKÜÇÜK ALPTUG EREN,Azim Muhammad Mohsin,Lokhat David,Rafatullah Mohd,Ganash Magdah (2018). Essential Oils: Extraction Techniques, Pharmaceutical And Therapeutic Potential - A Review. Current Drug Metabolism, 19(13), 1100-1110., Doi: 10.2174/1389200219666180723144850.

15. KARAKÜÇÜK ALPTUG EREN,ÇELEBI FATMA NEVIN,TEKSIN ZEYNEP SAFAK (2016). Preparation of ritonavir nanosuspensions by microfluidization using polymeric stabilizers: I. A Design of Experiment approach. European Journal of Pharmaceutical Sciences, 95, 111-121., Doi:10.1016/j.ejps.2016.05.010.

16. GÜLBAG SILA,YILMAZ USTA DUYGU,GÜLTEKIN HAZAL EZGI,OKTAY AYSE NUR,DEMIRTAS ÖZDEN,KARAKÜÇÜK ALPTUG EREN,ÇELEBI FATMA NEVIN (2016). New perspective to develop memantine orally disintegrating tablet formulations: SeDeM expert system. Pharmaceutical Development and Technology, 23(5), 512-519., Doi:10.1080/10837450.2017.1345941.

Ulusal hakemli dergilerde yayımlanan (TR Dizin) makaleler :

1. ÖZDEMİR SAMET, üNER BURCU, KARAKÜÇÜK ALPTUĞ (2023). Preparation and characterization studies of etodolac suppositories: investigation on oleaginous blends of Witepsol® H15. Journal of Research in Pharmacy 27 (2), 837-847.

2. TORT SERDAR, KARAKUCUK ALPTUG (2021). Serum Type Hyaluronic Acid Formulations: In vitro Characterization and Patch Test Study. FABAD Journal of Pharmaceutical Sciences, 46(3), 271-278. [Internet] http://dergi.fabad.org.tr/wp-content/uploads/2021/08/A-634.pdf

3. KARAKÜÇÜK ALPTUĞ EREN, TORT SERDAR (2021). Formulation, Optimization, and In-Vitro Evaluation of Hyaluronic Acid Buccal Films Containing Benzydamine Hydrochloride. Düzce Sağlık Bilimleri Enstitüsü Dergisi, 11(3), 325-330., DOI: 10.33631/duzcesbed.833024.

4. KARAKÜÇÜK ALPTUG EREN,TASHAN EMINE,ÖZTÜRK NAILE,ÇELEBI FATMA NEVIN (2021). In Vitro Caco-2 Cell Permeability Studies of Ziprasidone Hydrochloride Monohydrate Nanocrystals. Turkish Journal of Pharmaceutical Sciences, 18(2), 223-227., Doi:10.4274/tjps.galenos.2020.67366.

5. SARISALTIK YASIN DIREN,ARSLANTÜRK BINGÜL ALEV,KARAKÜÇÜK ALPTUG EREN,TEKSIN ZEYNEP SAFAK (2021). Development and validation of an HPLC method using an experimental design for analysis of amlodipine besylate and enalapril maleate in a fixed-dose combination. Turkish Journal of Pharmaceutical Sciences, 18(3), 306-318., Doi: 10.4274/tjps.galenos.2020.89725.

6. KARAKÜÇÜK ALPTUG EREN,ÖZTÜRK NAILE,ÇELEBI FATMA NEVIN (2020). Evaluation of Caco-2 cell permeability of ritonavir nanosuspensions. Istanbul Journal of Pharmacy, 50(3), 251-255.

7. TASHAN EMINE,KARAKÜÇÜK ALPTUG EREN,ÇELEBI FATMA NEVIN (2017). Orally Disintegrating Tablets: General Overview and Quality by Design Approach: Review. Turkiye Klinikleri Journal of Pharmacy Sciences, 6(1), 43-58., Doi: 10.5336/pharmsci.2017-54726.

Patentler :

1. Alptuğ Karaküçük, Nevin Çelebi, Serdar Tort, "Etodolak Nanosüspansiyonu İçeren Jel Formülasyonu", PCT/TR2021/050314, uluslararası patent (başvuru).

2. 22/10/2018, Serdar Tort, Alptuğ Karaküçük, Fiber Farma İlaç Kozmetik Tıbbi Cihazlar ve Danışmanlık Ltd. Şti. "Kitozan ve PVP Nanolifleri İçeren Kanama Durdurucu Örtü", 2016/16139, patent.

3. 21/06/2018, Nevin Çelebi, Emine Taşhan, Alptuğ Karaküçük, "Ziprasidon Hidroklorür Monohidrat (ZHM) Liyofilize Nanosüspansiyon Formülasyonu", 2017/03057 B, incelemeli patent.

4. 23/10/2017, Nevin Çelebi, Alptuğ Karaküçük, Zeynep Şafak Teksin, "Ritonavir İçeren Liyofilize Nanosüspansiyon Formülasyonu", 2016/02454 B, incelemeli patent.

5. 07/06/2016, Fiber Farma İlaç Kozmetik Tıbbi Cihazlar Eğitim ve Danışmanlık, "RESCARE", 2016/50333, Marka Tescili.

Projeler

1. "Etodolak Yüklü Nanoemülsiyonların Tasarımı Üzerine Çalışmalar", TÜBİTAK 1002, Proje Başlangıç Tarihi: 01.11.2021, Proje No: 221S147, Araştırmacı.

2. "Diklofenak Asitin Dermal Kullanımı için Nanosüspansiyon Yüklü Mikroiğne Geliştirilmesi", TÜBİTAK 2219 Yurtdışı Araştırma, Yürütücü (Beklemede).

3. "Nanosüspansiyon Bazlı Etodolak Jel Formülasyonunun Geliştirilmesi ve in vitro/ in vivo Değerlendirilmesi", TÜBİTAK 3001, Proje Başlangıç Tarihi: 15.05.2019, Proje Bitiş Tarihi: 24.07.2020, Proje No: 118S718, Proje Yürütücüsü.

4. "Siklosporinin Yeni Oral Formülasyonunun Geliştirilmesi ve İn vitro/ İn vivo Değerlendirilmesi", Gazi Üniversitesi Bilimsel Araştırma Projeleri, Proje Başlangıç Tarihi: 28.09.2017, Proje Bitiş Tarihi: 03.02.2020, Proje No 02/2017-14, Araştırmacı.

5. 2016/17 Newton Fund, Royal Academy of Engineering, Leaders In Innovation Fellowships, TÜBİTAK 2239, February 13-24, 2017, The Hoxton Holborn, London, UK.

6. "Saç Bakımında Bitkisel Kaynaklı Ürün Geliştirilmesi", PharmaSet Sağlık Ar-Ge,​ KOSGEB Ar-Ge ve İnovasyon Programı, Proje Başlangıç Tarihi: 2016, Proje Bitiş Tarihi: 2017, Proje Formülasyon ve Yazım Danışmanı (Fiber Farma).

7. "Nanokristal Teknolojisi Ile Ağızda Dağılan Tabletlerin Tasarımla Kalite (Qbd) Uygulamaları Ile Geliştirilmesi Ve Değerlendirilmesi", TÜBİTAK 1002, Proje Başlangıç Tarihi 2016, Proje Bitiş Tarihi: 2017, Proje No 215S920​, Bursiyer.

8. "Akneye Meyilli Ciltlerde ve Cilt Bakımında Etkili Yeni Nanoteknolojik Ürün Geliştirilmesi", Bilim, Teknoloji ve Sanayi Bakanlığı Teknogirişim Projesi, Proje Başlangıç Tarihi: 08/06/2015, Proje Bitiş Tarihi: 12/10/2016, Proje No 0104.TGSD, Proje Yürütücüsü.

9. "HIV Proteaz İnhibitörü Ritonavirin Yeni Nanosüspansiyon Formülasyonunun Geliştirilmesi ve İn Vitro/ İn Vivo Değerlendirilmesi", TÜBİTAK 1001, Proje Başlangıç Tarihi: 01/03/2014, Proje Bitiş Tarihi: 01/12/2016, Proje Yürütücüsü: Prof. Dr. Nevin Çelebi, Proje No 113S842, Bursiyer.

Ödüller

1. Gazi Üniversitesi Rektörlüğü Yayın Ödülü, 2020.
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​2. Gazi Üniversitesi Rektörlüğü Yayın ve Patent Ödülü, 2019.

3. Gazi Üniversitesi Rektörlüğü Patent Ödülü, 2018.

4. Gazi Üniversitesi Rektörlüğü Yayın Ödülü, 2017.

5. 2016/17 Final Pitch Session Third Place, Royal Academy of Engineering, Leaders In Innovation Fellowships, London, UK.

6. Gazi Üniversitesi Rektörlüğü Proje Ödülü, 2016.

7. İş Güvenliği ve Savunma Sanayine Yönelik Kanama Durdurucu Nanoteknolojik Örtü Geliştirilmesi, ​Gazi Üniversitesi Teknoloji Transfer Ofisi - Halkbank, Fikirden İcraata 2015, Birincilik Ödülü.
​
8. Akne ve Uçuk Tedavisinde Etkili Resveratrolün Kombine Yöntemlerle Yeni Nanofiber Formülasyonunun Geliştirilmesi, Gazi Üniversitesi Teknoloji Transfer Ofisi - Halkbank, Fikirden İcraata 2014, Birinci Mansiyon Ödülü.

Sözlü Bildiriler :

1. Alptug Karakucuk, "Pharmaceutical Technology Application as an Undergraduate Pharmacy Course in Distance Education Processes in Turkey", ERPA
International Congresses on Education 2023, September 8-10, 2023, Cunda- Balıkesir.

2. Alptug Karakucuk, Samet Ozdemir, Burcu Uner, "Preparation and characterization of resveratrol nanosuspension loaded orodispersible films", European Federation For Pharmaceutical Sciences (EUFEPS) Tenth Anniversary pan-European Science Conference on QbD&PAT, October 4-6, 2021, Virtual Science Conference.

3. Alptug Karakucuk, Samet Ozdemir, "Development of orodispersible films: QbD approach and future prospective", Global Summit on Drug Delivery, Discovery and Pharmaceutical Formulation, September 23, 2021, Virtual Science Conference.

4. Samet Ozdemir, Alptug Karakucuk, Burak Celik, "Lipid Screening Studies For The Development Of Etodolac Loaded Solid Lipid Nanoparticles (SLNs) and Nanostructured Lipid Carriers (NLCs)", III. International Aegean Symposiums on Natural & Medical Sciences, March 12-13, 2021, Izmir, Turkey.

5. Samet Ozdemir, Alptug Karakucuk, Burak Celik, "Design and evaluation of bioadhesive films for dental applications", 4th International Hippocrates Congress on Medical and Health Sciences, September 25-26, 2020, Antalya, Turkey.

6. Samet Ozdemir, Alptug Karakucuk, "Design and evaluation of oral mucoadhesive films for pharmaceuticals that have poor oral bioavailability", 4th International Medicine and Health Sciences Researchers Congress, August 22-23, 2020, Çorum, Turkey.

7. Alptug Karakucuk, "Solubility enhancement of poorly soluble drugs: A design of experiment approach to develop nanosuspensions", 23rd International Conference and Exhibition on Pharmaceutical Formulations, July 27-28, 2020, Webinar.

8. Diren Sarisaltik-Yasin, Alev Arslanturk-Bingul, Alptug Karakucuk, Zeynep Safak Teksin, "Development and validation of an HPLC method for amlodipine besylate and enalapril maleate using an experimental design and its application to solubility and dissolution tests", 12th of International Symposium on Pharmaceutical Sciences (ISOPS), June 26-29, 2018, Ankara, Turkey.

9. Sila Gulbag, Alptug Karakucuk, Basaran Mutlu-Agardan, Nevin Celebi, "Top-down production of cyclosporine A nanosuspensions for oral delivery: formulation design and characterization", European Federation For Pharmaceutical Sciences (EUFEPS) Annual Meeting 2018, May 24-26, 2018, Athens, Greece.
​
10. Serdar Tort, Alptug Karakucuk, "Akademik Girişimcilik", Davetli Konuşmacı, Gazi Üniversitesi Eczacılık Fakültesi FarmaEkol Öğrenci Topluluğu Sempozyumu (GaziFarmaSem), 30-31 Mart 2018, Ankara, Türkiye.

11. Aysenur Oktay, Alptug Karakucuk, Sibel Isbasmis-Tamer, Nevin Celebi, "Optimization of flurbiprofen nanosuspensions with polymeric stabilizers for dermal application", GPSS International Gazi Pharma Symposium Series 2, October 11-13, 2017, Ankara, Turkey.

12. Aysenur Oktay, Alptug Karakucuk, Sibel Isbasmis-Tamer, Nevin Celebi, "Optimization of flurbiprofen nanosuspensions: The QbD Approach", 7th BBBB International Conference on Pharmaceutical Sciences, October 5-7, 2017, Balatonfüred, Hungary.

13. Fiber Farma İl. Koz. Dan., "Kitozan ve PVP Kompozit Nanofiber Tabanlı Kanama Durdurucu Örtü Geliştirilmesi", Bio Startup Mena Hızlandırıcı Programı 2017 Dönemi, TEPAV, 25 Mayıs 2017, Ankara, Türkiye

14. Alptug Karakucuk, "Chitosan and PVP Composite Nanofiber Based Haemostatic Dressing", Royal Academy of Engineering, Leaders In Innovation Fellowships, February 13-24, 2017, London, UK.

15. Alptuğ Karaküçük, Nevin Çelebi, "Preparation of ritonavir nanosuspensions by microfluidization method using polymeric stabilizers: I. A design of experiment approach", 6th BBBB - Conference on Pharmaceutical Sciences: Strategies to Improve the Quality and Performance of Modern Drug Delivery Systems, September 10-12, 2015, Helsinki, Finland.

Poster Bildirileri:

1. Sila Gulbag, Alptug Karakucuk, Basaran Mutlu-Agardan, Nevin Celebi, "The Effect of Process Parameters of the Cyclosporine A Nanosuspension Produced by Wet Milling Stabilized with Hydroxypropyl methylcellulose", Controlled Release Society (CRS) Annual Meeting & Exposition, July 21-24, 2019, Valencia, Spain.

​2. Aysenur Oktay, Alptug Karakucuk, Sibel Isbasmis-Tamer, Nevin Celebi, "Optimization of Dermal Flurbiprofen Nanosuspension using Design of Experiment (DoE): Development by Wet Milling", AAPS PharmSci 360 Advancing Pharmaceutical Sciences, Carriers and Communities, November 4-7, 2018, Washington DC, USA.

3. Aysenur Oktay, Sibel Isbasmis-Tamer, Alptug Karakucuk, Nevin Celebi, "Evaluation of Dermal Permeation of Flurbiprofen-Nanosuspension Based Gel Systems, 19th. International Pharmaceutical Technology Symposium (IPTS)", September 17-19, 2018, Antalya/Turkey.

4. Emine Tashan, Alptug Karakucuk, Naile Ozturk, Nevin Celebi, "In-vitro Caco-2 Permeability Studies of Ziprasidone Hydrochloride Monohydrate Nanosuspensions", 19th International Pharmaceutical Technology Symposium (IPTS), September 17-19, 2018, Antalya, Turkey.

5. Sila Gulbag, Alptug Karakucuk, Basaran Mutlu-Agardan, Nevin Celebi, "Preformulation studies of cyclosporine A nanosuspension stabilized by hydroxypropyl methylcellulose and soluplus®", 12th of International Symposium on Pharmaceutical Sciences (ISOPS), June 26-29, 2018, Ankara, Turkey.

6. Aysenur Oktay, Alptug Karakucuk, Sibel Isbasmis-Tamer, Nevin Celebi, "The effect of polymeric stabilizer on stability of optimum flurbiprofen nanosuspension", 12th of International Symposium on Pharmaceutical Sciences (ISOPS), June 26-29, 2018, Ankara, Turkey.

7. Aysenur Oktay, Alptug Karakucuk, Sibel Isbasmis-Tamer, Nevin Celebi, "Evaluation of solubility and dermal permeation of flurbiprofen nanosuspension", European Federation For Pharmaceutical Sciences (EUFEPS) Annual Meeting 2018, May 24-26, 2018, Athens, Greece.

8. Alptug Karakucuk, Hakan Eroglu, Zeynep Safak Teksin, Nevin Celebi, "Preparation and analysis of in vitro- in vivo correlation of ritonavir nanosuspensions", European Federation For Pharmaceutical Sciences (EUFEPS) Annual Meeting 2018, May 24-26, 2018, Athens, Greece.

9. Sila Gulbag, Alptug Karakucuk, Basaran Mutlu-Agardan, Nevin Celebi, "Preparation and characterization of cyclosporine A nanosuspension for oral administration II: The effect of Poloxamer types on physical stability of formulations", 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, March 19-22, 2018, Granada, Spain.

10. Aysenur Oktay, Alptug Karakucuk, Sibel Isbasmis-Tamer, Nevin Celebi, "Optimization of flurbiprofen nanosuspensions using full factorial design for dermal application", 11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, March 19-22, 2018, Granada, Spain.

11. Sila Gulbag, Alptug Karakucuk, Nevin Celebi, "Preparation and characterization of cyclosporine nanosuspension for oral administration I: Effects of formulation parameters", GPSS International Gazi Pharma Symposium Series 2, October 11-13, 2017, Ankara, Turkey.

12. Merve Celik Tekeli, Alptug Karakucuk, Yesim Aktas, Nevin Celebi, "Development of a self-emulsifying drug delivery system by design of experiment (DoE) approach", GPSS International Gazi Pharma Symposium Series 2, October 11-13, 2017, Ankara, Turkey.

13. Emine Tashan, Alptug Karakucuk, Nevin Celebi, "Preparation of orally dispersible tablets of ziprasidone hydrochloride monohydrate nanocrystals: The Quality by Design (QbD) approach", 7th BBBB International Conference on Pharmaceutical Sciences, October 5-7, 2017, Balatonfüred, Hungary.​

14. Alptug Karakucuk, Zeynep Safak Teksin, Nevin Celebi, "Evaluation of fasted and fed bioavailabilities of ritonavir nanosuspension in rats", Controlled Release Society Annual Meeting & Exposition, July 16-19, 2017, Boston, Massachusetts, USA.

15. Alptug Karakucuk, Naile Ozturk, Imran Vural, Zeynep Safak Teksin, Nevin Celebi, "In vitro CACO-2 cell permeability studies of ritonavir nanosuspension formulation", 6th FIP Pharmaceutical Sciences World Congress 2017, May 21-24, 2017, Stockholm, Sweden.

16. Serdar Tort, Alptug Karakucuk, Nevin Celebi, Fusun Acarturk, "Electrospun PCL Nanofiber composites of resveratrol nanocrystals: Production, Characterization and Antimicrobial Activity", 6th FIP Pharmaceutical Sciences World Congress 2017, May 21-24, 2017, Stockholm, Sweden.

17. Alptug Karakucuk, Hande Canpinar, Nevin Celebi, "Determination of lymphocyte sub-groups after administration of ritonavir nanosuspensions orally using flow cytometry", The 22nd Biomedical Science and Technology Symposium (BIOMED 2017), May 12-14, 2017, Ankara, Turkey.

18. Emine Taşhan, Alptuğ Karaküçük, Nevin Çelebi, "Evaluation of Solubility and Dissolution Profiles of Ziprasidone Hydrochloride Monohydrate Nanosuspensions", 18th International Pharmaceutical Technology Symposium (IPTS), September 18-21, 2016, Antalya, Turkey.

19. Alptug Karakucuk, Nevin Celebi, Zeynep Teksin, "Evaluation of solubility and dissolution of ritonavir nanosuspensions", 4th Congress on Innovation in Drug Delivery Site-Specific Drug Delivery, September 25-28, 2016, Antibes-Juan-les-Pins, France.

20. Alptuğ Karaküçük, Nevin Çelebi, "Characterization and optimization of ritonavir nanosuspension formulations using different stabilizers: III. Application of the factorial design", 10th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, April 4-7, 2016, Glasgow, United Kingdom.

21. Ayşe Nur Oktay, Sıla Gülbağ, Özden Demirtaş, Duygu Yılmaz Usta, Hazal Ezgi Gültekin, Alptuğ Eren Karaküçük, Nevin Çelebi "New Perspective For Memantine Orally Disintegrating Tablet: SeDeM Expert System", GPSS International Gazi Pharma Symposium Series, November 12-15, 2015, Antalya, Turkey.

22. Alptuğ Karaküçük, Nevin Çelebi, "Preparation and Characterization of HPMC Stabilized Nanosuspensions: II. Considering Interactions Between Formulation Parameters", 2015 AAPS Annual Meeting and Exposition, October 25-29, 2015, Orlando, USA.

23. Emine Taşhan, Alptuğ Karaküçük, Nevin Çelebi, "Preparation of Ziprasidone Hydrochloride Monohydrate Nanosuspensions Through Desing of Experiment (DoE)", 2015 AAPS Annual Meeting and Exposition, October 25-29, 2015, Orlando, USA.

24. Alptuğ Karaküçük, Nevin Çelebi, Zeynep Şafak Teksin, “Effect of stabilizers on the particle size reduction and physical stability of ritonavir nanosuspensions” 2014 AAPS Annual Meeting and Exposition, November 2-6, 2014, San Diego, USA.

25. Emine Taşhan, Alptuğ Karaküçük, Nevin Çelebi, “Preparation of ziprasidone nanosuspensions by microfluidization technique using different stabilizers”, 17th International Pharmaceutical Technology Symposium (IPTS), September 8-10, 2014, Antalya, Turkey.

26. Gülen Melike Demir, Alptuğ Karaküçük, Zelihagül Değim, Derya Bektaş, Özlem Çoban, Ezgi Gülpınar, Sema Tuna Torunoğlu, “Stirring Speed Effects On Physical Characteristics Of Theophylline Microsphere”, Proceedings of the 5th International Conference on Nanotechnology: Fundamentals and Applications August 11-13, 2014, Prague, Czech Republic.


GAZI UNIVERSITY FACULTY OF ARTS AND SCIENCES 1994 GAZI UNIVERSITY GRADUATE SCHOOL OF NATURAL AND APPLIED SCIENCES GAZI UNIVERSITY GRADUATE SCHOOL OF NATURAL AND APPLIED SCIENCES

Previous Positions

Republic of Türkiye Ministry of Health
Hitit University

Research Areas

Food Microbiology,
Water Microbiology,
Cosmetic Microbiology,
Microbiological Efficacy Tests,
Quality Management System-Accreditation

Selected Publications / All Publications

MAKALE
GÜNAYDIN ELÇİN, MURSALOĞLU KAYNAR PINAR, ESENER ASLI, KUL İSA, BAYINDIR BİLMAN FULYA, MÜDERRİS TUBA. Antibiotic Resistance Profile of Salmonella Enterica Subsp. Enterica Isolated From Dog And Human Samples In Türkiye: The Case of Kastamonu. Acta Veterinaria-Beograd, 2024; 74 (2): 285-301.
NUMANOĞLU ÇEVİK YASEMİN, MURSALOĞLU KAYNAR PINAR (2023). Contribution of MALDI‐TOF‐MS ‐based principal component analysis for distinguishing foodborne pathogens. Journal of Food Safety, Doi: 10.1111/jfs.13053.
MURSALOĞLU KAYNAR PINAR, DEMLİ FİGEN, ORHAN GÜNNUR, İLTER HÜSEYİN (2022). Chemical and microbiological assessment of drinking water quality. African Health Sciences, Doi: 10.4314/ahs.v22i4.70.
MURSALOĞLU KAYNAR PINAR, NUMANOĞLU ÇEVİK YASEMİN (2021). Microbiological evaluation of ready-to-eat foods by conventional methods and MALDI-TOF MS. Journal of The Hellenic Veterinary Medical Society, 72(2), 2825-2832. Doi: 10.12681/jhvms.27518.
KAYNAR PINAR (2020). Determination of microbiological properties of milk-based desserts presented for consumption in Ankara, Turkey. Journal of Food Safety and Food Quality-Archiv fur Lebensmittelhygiene, 71(4), 93-97. Doi: 10.2376/0003-925X-71-93.
KAYNAR PINAR (2017). Antimicrobial activity of quercus robur L. (acorn). Fresenius Environmental Bulletin, 26(12), 6992-6995.
KAYNAR PINAR, BEYATLI YAVUZ (2009). Determination of poly-β-hydroxybutyrate production by Bacillus spp. isolated from the intestines of various fishes. Fisheries Science, 75(2), 439-443., Doi: 10.1007/s12562-008-0047-z.
KAYNAR PINAR, BEYATLI YAVUZ (2008). Protein profiles and biochemical characterizations of Bacillus spp. strains isolated from fishes. Fresenius Environmental Bulletin, 17, 1316-1321.
KAYNAR PINAR, BEYATLI YAVUZ (2007). Metabolic and antimicrobial activities of Lactobacıllus spp. strains isolated from anchovy (Engraulis encrasichalus). Fresenius Environmental Bulletin, 16(6), 608-612.
MURSALOĞLU KAYNAR PINAR, GÜNAYDIN ELÇİN (2023). Microbiological Evaluation of Foods for Special Medical Purposes of Children. Turkish Journal of Agriculture- Food Science and Technology, Doi: 10.24925/turjaf.v11i8.1360-1364.6079.
YILDIRIM FİLİZ, ÖZTÜRK REYHAN, MURSALOĞLU KAYNAR PINAR, YILDIRIM ZUHAL, KARAGEÇİLİ HASAN (2023). Evaluation of Infection Factor and Antibiotic Resistance Distributions in Palliative Care Patients Developed Urinary Tract Infection. Gazi University Faculty of Medicine, 34, Doi: 10.12996/gmj.2023.64.
GÜNAYDIN ELÇİN, GONCAGÜL GÜLŞEN, MURSALOĞLU KAYNAR PINAR (2023). Repeat breeder ineklerde genital kanal bakteriyolojisi ve antibiyotik direnç profilleri. Türk Hijyen ve Deneysel Biyoloji Dergisi (Yayın No: 8723522)
GÜNAYDIN ELÇİN, KARDOĞAN ÖZLEM, GONCAGÜL GÜLŞEN, ÇOKAL YAVUZ, MURSALOĞLU KAYNAR PINAR (2022). Salmonella Typhimurium and Salmonella Hessarek in wild birds. Türk Hijyen ve Deneysel Biyoloji Dergisi, 79(4), 740-747. Doi: 10.5505/TurkHijyen.2022.34538.
KAYNAR MURSALOĞLU PINAR (2020). Su laboratuvarlarının TS EN ISO/IEC standart revizyonu ile değişimleri. Türk Hijyen ve Deneysel Biyoloji Dergisi, 77(EK4: Su ve Sağlık): 57-64. Doi: 10.5505/TurkHijyen.2020.79027.
KAYNAR PINAR, ŞENSES MUKADDES, KARACA SİBEL, CESARETLİ YILDIRIM (2018). TS EN ISO/IEC 17025 standart kapsamında akredite olan su laboratuvarlarında müşteri memnuniyetinin değerlendirilmesi. Türk Hijyen ve Deneysel Biyoloji Dergisi, 75(2), 143-152.10.5505/TurkHijyen.2018.74508.
ŞENSES ERGÜL ŞULE, KAYNAR PINAR, YILMAZ MUSTAFA, CESARETLİ YILDIRIM, BAŞARALI MUSTAFA KEMAL, ŞENCAN İRFAN (2017). İçme kullanma sularındaki Cryptosporidium ookist ve Giardia kistlerinin analizinde TS ISO 15553 standart yönteminin uygulanabilirliğinin dış kalite kontrol numunesi ile değerlendirilmesi. Türk Hijyen ve Deneysel Biyoloji Dergisi, 74, 7-12., Doi: 10.5505/TurkHijyen.2017.56514.
KAYNAR PINAR, YILMAZ MUSTAFA, SEMİZOĞLU ÖZGÜL, ERİŞ ZEHRA İREM, KARADENİZ DURSUN FATMA, CESARETLİ YILDIRIM, BAŞARALI MUSTAFA KEMAL, ŞENCAN İRFAN (2017). Su örneklerinde norovirüs varlığının cross-flow mikrofiltrasyon ve RT-PCR ile belirlenmesi. Türk Hijyen ve Deneysel Biyoloji Dergisi, 74, 1-6., Doi: 10.5505/TurkHijyen.2017.6769.
SAĞDIÇOĞLU CELEP ADVİYE GÜLÇİN, KAYNAR PINAR, RASTMANESH REZA (2017). Biochemical Functions of Micronutrients. Advances in Obesity, Weight Management Control, 6(2), 1-4., Doi: 10.15406/aowmc.2017.06.00147.
KAYNAR PINAR, KAVAKLI AYŞE, CESARETLİ YILDIRIM, IRMAK HASAN (2014). Özel tıbbi amaçlı diyet gıdaların besin öğesi içerikleri yönünden incelenmesi. Türk Hijyen ve Deneysel Biyoloji Dergisi, 71(1), 9-18., Doi: 10.5505/TurkHijyen.2014.93899.
KAYNAR PINAR (2013). Quantitative determination of vitamin B6 in dietary foods for special medical purposes by micribiological assay method. African Journal of Microbiology Research, 7(27), 3489-3493., Doi: 10.5897/AJMR12.1641.
KAYNAR PINAR, BEYATLI YAVUZ (2012). Antagonistic Activities of Bacillus spp. Strains Isolated from the Fishes. Journal of Applied Biological Sciences, 6(3), 77-81.
KAYNAR PINAR, CANPOLAT MEŞKÜRE, KAVAKLI AYŞE, OZEROGLU ESRA JALE, SUBASİ SERDAR ALP (2012). Enteral beslenme ürünlerindeki toplam vitamin C miktarlarının HPLC ile belirlenmesi. Türk Hijyen ve Deneysel Biyoloji Dergisi, 69(3), 143-148. Doi: 10.5505/TurkHijyen.2012.80037
KAYNAR PINAR (2011). Ülkemiz peynirleri üzerine mikrobiyolojik araştırmalar. Türk Mikrobiyoloji Cemiyeti Dergisi, 44(1), 1-8. Doi: 10.5222/TMCD.2011.001.
KAYNAR PINAR (2010). Genetik Olarak Değiştirilmiş Organizmalar (GDO)’ya Genel Bir Bakış. Türk Hijyen ve Deneysel Biyoloji Dergisi, 66(4), 177-186.
KAYNAR PINAR, CANPOLAT MEŞKÜRE, BİNGÖL MEHMET, POLAT AYNUR (2007). Enteral beslenme ürünlerindeki vitamin B2 miktarlarının HPLC ile belirlenmesi. Türk Hijyen ve Deneysel Biyoloji Dergisi, 64(3), 5-9.
KAYNAR PINAR, YILMAZ IŞIK (2006). Gıda kaynaklı zehirlenmelerde patojen bakterilerin tanısı: 2002-2003 yılları arasında incelenen vakaların mikrobiyolojik değerlendirilmesi. Gıda Mühendisliği Dergisi (23), 33-39.
KAYNAR PINAR, BEYATLI YAVUZ (2006). Balıklardan İzole Edilen Bacillus Cinsi Bakterilerin Bazı Metabolik Özelliklerinin Belirlenmesi, Plazmid DNA ve Protein Profillerinin İncelenmesi. Orlab on-line mikrobiyoloji dergisi, 4(3), 1-30.
KAYNAR ZEYNAL, KAYNAR PINAR, KOÇAK CELALETTİN (2005). Ankara piyasasında tüketime sunulan beyaz peynirlerin hijyenik kalitelerinin belirlenmesi üzerine bir araştırma. Türk Hijyen ve Deneysel Biyoloji Dergisi, 62, 1-9.
KAYNAR PINAR (2019). Gıda hijyeni. Standart, 677, 45-49.
KAYNAR PINAR (2008). Enteral beslenme ürünleri, özel tıbbi amaçlı diyet gıdaları ve tıbbi amaçlı bebek mamalarının 2007 yılına ait verilerinin değerlendirilmesi. Türk Hijyen ve Deneysel Biyoloji Dergisi, 65, 8-9.
KİTAP
Sağlık Teknikerleri İçin İş Sağlığı ve Güvenliği, Bölüm adı:(İş Hijyeni) (2024). MURSALOĞLU KAYNAR PINAR, BABAOĞLU AYDAŞ SENİHA SELCEN., Nobel Akademik Yayıncılık, Basım sayısı:1, Sayfa Sayısı 206, ISBN:978-625-371-192-4, Türkçe (Bilimsel Kitap)
KAYNAR MURSALOĞLU PINAR. Fen Bilimleri ve Matematik Alanında Akademik Araştırma ve Derlemeler Bölüm adı: (Sularda Salmonella Spp. Aranması) (2021). Duvar Yayınları, Editör: Dr. Öğr. Üyesi Mine SULAK, Basım sayısı:1, Sayfa Sayısı 44, ISBN:978-625-7680-62-2, Türkçe (Bilimsel Kitap)
KAYNAR MURSALOĞLU PINAR. Fen Bilimleri ve Matematik Alanında Güncel Çalışmalar, Bölüm adı: (Çevre Mikrobiyolojisi Laboratuvarlarında Atık Yönetimi) (2021). Duvar Yayınları, Editör: Prof. Dr. Hüsniye SAĞLIKER, Basım sayısı:1, Sayfa Sayısı 57, ISBN:978-625-7502-02-3, Türkçe (Bilimsel Kitap)
TEBLİĞ (BİLDİRİ)
MURSALOĞLU KAYNAR PINAR. (2024). Zoonoz hastalıklar: Çiftlikten Sofraya Gıda Güvenliği. IV. ULUSAL TARIM VE GIDA ÇALIŞTAYI (Özet bildiri/Sözlü Sunum)
MURSALOĞLU KAYNAR PINAR. (2023). Arı ürünlerinin insan sağlığı açısından önemi. ARICILIK PANELİ. (Davetli Konuşmacı)
MURSALOĞLU KAYNAR PINAR (2023). Tıbbi cihazların ve ürünlerinin değerlendirilmesinde mikrobiyolojik testlerin önemi. 6th International Eurasian Conference on Biological and Chemical Sciences (Özet Bildiri/Sözlü Sunum)
MURSALOĞLU KAYNAR PINAR, ŞİMŞEK HÜLYA, CEYHAN İSMAİL, KIRBAŞ ELİF (2021). The standardization activities in our country during covid-19 pandemic. 3rd International Symposium On Global Pandemics And Multidiscipliınary Covid-19 Studies (Tam Metin Bildiri/Sözlü Sunum)
MURSALOĞLU KAYNAR PINAR, ŞİMŞEK HÜLYA, CEYHAN İSMAİL, KIRBAŞ ELİF (2021). TS 13811 standard: a novel approach to hygiene management in public areas. I. International Hygiene Conference (Tam Metin Bildiri/Sözlü Sunum)
MURSALOĞLU KAYNAR PINAR (2021). Su Örneklerinde Salmonella spp. saptanmasında Kullanılan Yöntemlerin Değerlendirilmesi. 4. Uluslararası Tarım, Çevre Ve Sağlık Kongresi (Özet Bildiri/Sözlü Sunum)
KAYNAR PINAR (2020). Bir Tavuk İşletmesindeki İçme Suyunun Salmonella Spp. Yönünden İncelenmesi. 4. Uluslararası Tıp ve Sağlık Bilimleri Araştırmaları Kongresi (Tam Metin Bildiri/Sözlü Sunum)
KAYNAR PINAR (2020). Fen Bilimleri Laboratuvarlarında Güvenlik. I. Uluslararası Bilimsel Araştırmalar Kongresi (Tam Metin Bildiri/Sözlü Sunum)
KAYNAR PINAR (2019). Su Laboratuvarlarının TS EN ISO/IEC 17025 Standart Revizyonu İle Değişimleri. 3. Uluslararası Su ve Sağlık Kongresi (Tam Metin Bildiri/Sözlü Sunum)
KAYNAR PINAR (2019). The importance of the safety of water in terms of microbiological for healty life. 5th International Eurasian Congress on Natural Nutrition, Healthy Life Sport (Özet Bildiri/Sözlü Sunum)
ŞENSES ERGÜL ŞULE, KAYNAR PINAR, YILMAZ MUSTAFA, CESARETLİ YILDIRIM, BAŞARALI MUSTAFA KEMAL, ŞENCAN İRFAN (2017). İçme kullanma sularındaki Cryptosporidium ookist ve Giardia kistlerinin analizinde TS ISO 15553 standart yönteminin uygulanabilirliğinin dış kalite kontrol numunesi ile değerlendirilmesi. 2. Uluslararası Su Ve Sağlık Kongresi (Tam Metin Bildiri/Sözlü Sunum)
KAYNAR PINAR, SEMİZOĞLU ÖZGÜL, YILMAZ MUSTAFA, ERİŞ ZEHRA İREM, KARADENİZ DURSUN FATMA, CESARETLİ YILDIRIM, BAŞARALI MUSTAFA KEMAL, ŞENCAN İRFAN (2017). Su örneklerinde norovirüs varlığının cross-flow mikrofiltrasyon ve RT-PCR ile belirlenmesi. 2. Uluslararası Su ve Sağlık Kongresi (Tam Metin Bildiri/Sözlü Sunum)
OKKALI TANER, ELMACI EMİN, KAYNAR PINAR, SUBASİ SERDAR ALP (2012). Özel tıbbi amaçlı diyet gıdalardaki sodyum, potasyum, kalsiyum, magnezyum ve fosfor miktarlarının ICP-OES ile belirlenmesi. Intenational Food, Agriculture and Gastronomy Congress (Özet Bildiri/Poster)
ÇELİKTEN BERKAN, KAYNAR PINAR, ZIRAMAN FATMA GÜL, DUZGUN ZD, CALI AA (2010). Evaluation of three different resin based root canal sealers regarding coranal bacterial leakage. 10th International Congress of the Turkish Endodontic Society (Özet Bildiri/Poster)
KAYNAR PINAR, CANPOLAT MEŞKÜRE, BİNGÖL MEHMET, OZEROGLU ESRA JALE, SUBASİ SERDAR ALP (2009). Determination of vitamin B6 (pyridoxine) in liquid enteral nutrition products by microbiological assay method. 3rd International Congress on Food and Nutrition (Özet Bildiri/Poster)
KAYNAR PINAR, CANPOLAT MEŞKÜRE, BİNGÖL MEHMET, POLAT AYNUR (2007). Enteral beslenme ürünlerindeki vitamin B2 miktarının HPLC ile belirlenmesi. IX. Uluslararası Katılımlı Beslenme ve Metabolizma Kongresi (Özet Bildiri/Poster)
MURSALOĞLU KAYNAR PINAR (2023). Gıda Ve Yem Alanlarında Kullanılan Biyosidal Ürün Tipi: Dezenfektanlar. III. ULUSAL TARIM VE GIDA ÇALIŞTAYI (Özet Bildiri/Sözlü Sunum)
MURSALOĞLU KAYNAR PINAR (2022). Tüketici Bakış Açısıyla Sürdürülebilir Gıda ve Sağlık. II. ULUSAL TARIM VE GIDA ÇALIŞTAYI SÜRDÜRÜLEBİLİRLİK, 30-30. (Özet Bildiri/Sözlü Sunum)
MURSALOĞLU KAYNAR PINAR (2021). Gıda işletmelerinde su güvenliği. ULUSAL TARIM VE GIDA ÇALIŞTAYI (Özet Bildiri/Sözlü Sunum)
KAYNAR PINAR, ŞENSES MUKADDES, KARACA SİBEL, CESARETLİ YILDIRIM (2018). TS EN ISO/IEC 17025 standart kapsamında akredite su laboratuvarlarındaki personelin yeterlilik süreci. 4. ULUSAL LABORATUVAR AKREDİTASYONU VE GÜVENLİĞİ SEMPOZYUMU VE SERGİSİ (Özet Bildiri/Poster)
KAYNAR PINAR, YILMAZ MUSTAFA, CESARETLİ YILDIRIM (2015). Su Mikrobiyoloji Laboratuvarında Biyogüvenlik. ULUSAL SU VE SAĞLIK KONGRESİ (Özet Bildiri/Poster)
BÖCÜKCÜ ADEM, KAYNAR PINAR, SAĞDIÇOĞLU CELEP ADVİYE GÜLÇİN (2014). Ankara ilinde bulunan organik ürün pazarlarında geleneksel gıdaların yeri. 4.GELENEKSEL GIDALAR SEMPOZYUMU (Tam Metin Bildiri/Poster)
KAYNAR PINAR, ARSLANTÜRK BETÜL, ATAKAN ABLAY PINAR, BERBEROĞLU UMUT, CESARETLİ YILDIRIM, IRMAK HASAN (2014). Kaplıca sularının mikrobiyolojik yönden değerlendirilmesi. III. DİSİPLİNLERARASI TURİZM ARAŞTIRMALARI KONGRESİ (Tam Metin Bildiri/Sözlü Sunum)
KAYNAR PINAR, KAVAKLI AYŞE, CESARETLİ YILDIRIM, Irmak Hasan (2014). Besin alerjisi olan bebek ve çocukların beslenmesinde kullanılan özel tıbbi amaçlı beslenme ürünlerinin besin öğesi içerikleri yönünden değerlendirilmesi. 2. FETAL HAYATTAN ÇOCUKLUĞA İLK 1000 GÜN GEBE VE ÇOCUK BESLENMESİ KONGRESİ (Özet Bildiri/Sözlü Sunum)
KAYNAR PINAR, KAVAKLI AYŞE, CESARETLİ YILDIRIM, IRMAK HASAN (2013). Özel tıbbi amaçlı diyet gıdaların besin öğesi içerikleri yönünden incelenmesi. 4. GIDA GÜVENLİĞİ KONGRESİ (Özet Bildiri/Poster)
KAYNAR PINAR, KAVAKLI AYŞE, SARI HAVVA, ORHAN GÜLNUR, CESARETLİ YILDIRIM, IRMAK HASAN (2013). Probiyotik ve FOS içerikli tıbbi amaçlı beslenme ürünlerinin bazı kimyasal ve mikrobiyolojik özellikleri ile afla toksin varlığının araştırılması. Uluslararası Katılımlı 1. ULUSAL PROBİYOTİK PREBİYOTİK VE FONKSİYONEL GIDALAR KONGRESİ (Özet Bildiri/Poster)
KAYNAR PINAR, CANPOLAT MEŞKÜRE, KAVAKLI AYŞE, OZEROGLU ESRA JALE, SUBASİ SERDAR ALP (2011). Enteral beslenme ürünlerindeki toplam vitamin C miktarının HPLC ile belirlenmesi. Hacettepe Beslenme ve Diyetetik Günleri III. MEZUNİYET SONRASI EĞİTİM KURSU (Özet Bildiri/Poster) (Ya5433110)
KAYNAR PINAR, EMEK MESTAN (2010). Sağlık alanında görev yapan personelin genetiği değiştirilmiş organizmalarla (GDO’larla) ilgili bilgi ve tutumları. 2. GIDA GÜVENLİĞİ KONGRESİ (Özet Bildiri/Sözlü Sunum) (Yayın No: 5433897)
CANPOLAT MEŞKÜRE, KAYNAR PINAR, KAVAKLI AYŞE, ÖZEROĞLU ESRA JALE, SUBAŞI SERDAR ALP (2010). Özel tıbbi amaçlı beslenme ürünlerindeki E vitamini miktarlarının HPLC ile belirlenmesi. 2. Gıda Güvenliği Kongresi (Özet Bildiri/Poster)
KAYNAR PINAR, YILMAZ IŞIK (2004). - Gıda kaynaklı zehirlenmelerde patojen bakterilerin tanısı: 2002-2003 yılları arasında incelenen vakaların mikrobiyolojik değerlendirilmesi. - XXXI. Türk MİKROBİYOLOJİ KONGRESİ (Özet Bildiri/Poster)
EDİTÖRLÜK
PINAR MURSALOĞLU KAYNAR, HASAN IRMAK, eds. Su ve Sağlık. (2020). Türk Hijyen ve Deneysel Biyoloji Dergisi.
PINAR MURSALOĞLU KAYNAR, EDİBE NURZEN BOZKURT, eds. Laboratuvar Güvenliği El Kitabı (2019). Ankara: Sağlık Bakanlığı Yayın No : 1114.
HASAN IRMAK, PINAR KAYNAR, eds. 2. Uluslararası Su Ve Sağlık Kongresi. (2017). Türk Hijyen ve Deneysel Biyoloji Dergisi.

Ankara University 2017 Ankara University Ankara University

Previous Positions

Ankara University Faculty of Pharmacy - Clinical Pharmacy Residency

Research Areas

Selected Publications / All Publications

Gazi University 2009 Hacettepe University Hacettepe University

Previous Positions

Hacettepe University
Baskent University

Research Areas

Analytical Chemistry
Electrochemistry
Metabolomics
Gas Chromatography-Mass Spectrometry
Liquid Chromatography-Mass Spectrometry
Nanosensors
Metabolites
Molecular Imprinted Polymer
High Performance Liquid Chromatography
Drug Analysis
Biosensors

Selected Publications / All Publications

Ankara University Ankara University Ankara University

Previous Positions

Research Areas

Cancer biochemistry, Cell death mechanisms, Cell signaling, Chemotherapeutics, Antioxidants

Selected Publications / All Publications

Uluslararası hakemli dergilerde yayımlanan makaleler (WOS/SCOPUS):
 Bakar-Ates, F., Ozkan, E. Synergistic ferroptosis in triple-negative breast cancer cells: Paclitaxel in combination with Erastin induced oxidative stress and Ferroportin-1 modulation in MDA-MB-231 cells. Naunyn-Schmiedeberg's Arch Pharmacol 398, 3985–3994 (2025). https://doi.org/10.1007/s00210-024-03523-8

 Kaya SG, Eren G, Massarotti A, Gunindi HB, Bakar-Ates F, Ozkan E. Symmetrical 2,7-disubstituted 9H-fluoren-9-one as a novel and promising scaffold for selective targeting of SIRT2. Arch Pharm (Weinheim). 2024;357(12):e2400661. http://doi.org/10.1002/ardp.202400661

 Kaya SG, Eren G, Massarotti A, Bakar-Ates F, Ozkan E, Gozelle M, Ozkan Y. 2-(Methyl(phenyl)amino)-N-(phenyloxyphenyl)acetamide structural motif representing a framework for selective SIRT2 inhibition. Drug Dev Res. 2024;85(4):e22224. http://doi.org/10.1002/ddr.22224

 Gozelle, M., Bakar-Ates, F., Massarotti, A., Ozkan, E., Gunindi, H. B., Ozkan, Y., & Eren, G. (2023). In silico approach reveals N-(5-phenoxythiophen-2-yl)-2-(arylthio)acetamides as promising selective SIRT2 inhibitors: the case of structural optimization of virtual screening-derived hits. Journal of Biomolecular Structure and Dynamics, 43(4), 1756–1767. https://doi.org/10.1080/07391102.2023.2293252

 Bakar-Ates F, Ozkan E. Cucurbitacin B and erastin co-treatment synergistically induced ferroptosis in breast cancer cells via altered iron-regulating proteins and lipid peroxidation. Toxicol In Vitro. 2024;94:105732. http://doi.org/10.1016/j.tiv.2023.105732

 Ozkan E, Bakar-Ates F. Cuproptosis as the new kryptonite of cancer: a copper-dependent novel cell death mechanism with promising implications for the treatment of hepatocellular carcinoma. J Cancer Res Clin Oncol. 2023;149(19):17663-17670. http://doi.org/10.1007/s00432-023-05456-w

 Gultekin, I., Ozkan, E., Bakar Ateş, F., & Bozdağ Dündar, O., (2023). New Flavone Derivatives Targeting BET Proteins in Cancer: Synthesis, Structure Analysis and Investigation of Bromodomain Inhibitory Activities. CHEMISTRYSELECT , vol.8, no.41.

 Topal, G. R., Küçüktürkmen, B., Öz, U. C., Ozkan, E., Bakar Ateş, F., & Bozkır, A., (2023). Investigation on formulation parameters of donepezil HCl loaded solid lipid nanoparticles. Braz. J. Pharm. Sci. 59, 2023, https://doi.org/10.1590/s2175-97902023e22330

 Ozkan E, Bakar-Ates F. Etoposide in combination with erastin synergistically altered iron homeostasis and induced ferroptotic cell death through regulating IREB2/FPN1 expression in estrogen receptor positive-breast cancer cells. Life Sci. 2023;312:121222. http://doi.org/10.1016/j.lfs.2022.121222

 Bakar-Ates F, Ozkan E. Atorvastatin induces downregulation of matrix metalloproteinase-2/9 in MDA-MB-231 triple negative breast cancer cells. Med Oncol. 2022;40(1):22. Published 2022 Nov 29. http://doi.org/10.1007/s12032-022-01880-z

 Sengel-Turk CT, Ozkan E, Bakar-Ates F. Box-Behnken design optimization and in vitro cell based evaluation of piroxicam loaded core-shell type hybrid nanocarriers for prostate cancer. J Pharm Biomed Anal. 2022;216:114799. http://doi.org/10.1016/j.jpba.2022.114799

 Gozelle M, Kaya SG, Aksel AB, Ozkan E, Bakar-Ates F, Ozkan Y, Eren G. Hit evaluation results in 5-benzyl-1,3,4-thiadiazole-2-carboxamide based SIRT2-selective inhibitor with improved affinity and selectivity. Bioorg Chem. 2022;123:105746. http://doi.org/10.1016/j.bioorg.2022.105746

 Ozkan E, Bakar-Ates F. Ferroptosis: A Trusted Ally in Combating Drug Resistance in Cancer. Curr Med Chem. 2022;29(1):41-55. http://doi.org/10.2174/0929867328666210810115812

 Bakar-Ates F, Ozkan E, Sengel-Turk CT. Encapsulation of cucurbitacin B into lipid polymer hybrid nanocarriers induced apoptosis of MDAMB231 cells through PARP cleavage. Int J Pharm. 2020;586:119565. http://doi.org/10.1016/j.ijpharm.2020.119565

 Ozkan E, Bakar-Ates F. Potentiation of the Effect of Lonidamine by Quercetin in MCF-7 human breast cancer cells through downregulation of MMP-2/9 mRNA Expression. An Acad Bras Cienc. 2020;92(4):e20200548. Published 2020 Nov 20. http://doi.org/10.1590/0001-3765202020200548

 Ozkan E, Bakar-Ates F. The Trinity of Matrix Metalloproteinases, Inflammation, and Cancer: A Literature Review of Recent Updates. Antiinflamm Antiallergy Agents Med Chem. 2020;19(3):206-221. http://doi.org/10.2174/1871523018666191023141807

 Bakar-Ates F, Ozkan E. The combined treatment of brassinin and imatinib synergistically downregulated the expression of MMP-9 in SW480 colon cancer cells. Phytother Res. 2019;33(2):397-402. http://doi.org/10.1002/ptr.6233


Uluslararası Hakemli Kitaplarda Yayımlanan Kitap Bölümü:
 Ozkan E & Bakar-Ates F. 2022. Resistin: An Irresistible Therapeutic Target for Inflammatory Diseases, Allergy-Related Disorders, and Cancer. In A.-U. Rahman (Ed.), Frontiers in Clinical Drug Research – Anti Allergy Agents (5th vol., pp. 1-40). Bentham Science. http://doi.org/10.2174/9789815040616122050003


Sözlü Bildiriler:
 X. Multidisciplinary Cancer Research Congress, 8-11 Mayıs 2025, Eskişehir-Türkiye
Bildiri Başlığı: Ozkan E, Elmazoglu Z. Reviving the Classics: Venetoclax Sensitizes Lung Cancer Cells to Conventional Chemotherapeutics via Ferroptotic Pathways and DNA damage

 X. Multidisciplinary Cancer Research Congress, 8-11 Mayıs 2025, Eskişehir-Türkiye
Bildiri Başlığı: Elmazoglu Z, Ozkan E. Uncovering A Novel Mechanism of Cucurbitacin B: Short-Term Exposure Demonstrates Disulfidptosis-Like Cell Death in Lung Cancer Cells

 XXXI. Balkan Klinik Laboratuvar Federasyonu ve 35. Ulusal Biyokimya Kongresi, 28 Ekim - 1 Kasım 2024, Antalya-Türkiye
Bildiri Başlığı: Ozkan E, Elmazoglu Z. Cannabinomimetics Induce Ferroptosis Via Lipid Accumulation and Upregulated Transferrin Receptor Gene Expression In Human Glioblastoma Cells

 The 14th International Symposium on Pharmaceutical Sciences (ISOPS 2024) –Ankara
Bildiri Başlığı: Elmazoglu, Z., Ozkan, E. Venetoclax Targets Human Neuroblastoma Cells via Alteration of Iron Homeostasis and Lipotoxicity.

 The 14th International Symposium on Pharmaceutical Sciences (ISOPS 2024) –Ankara
Bildiri Başlığı: Ozkan, E., Elmazoglu, Z. The Synthetic Cannabinoids CP55-940 and WIN 55212-2 Induced Iron Dysregulation and Oxidative Stress in Human Glioblastoma Cells.

 3rd International Multidisciplinary Cancer Research Congress, Istanbul, Turkiye. 07-10 September 2023.
Bildiri Başlığı: Ozkan, E., Bakar-Ates, F. The Anticancer Potential of Brassinin In Estrogen Receptor-Positive Breast Cancer Cells Through The Activation Of Apoptosis And Downregulation Of Matrix Metalloproteinase-2

 The 12nd International Symposium on Pharmaceutical Sciences (ISOPS 2018) –Ankara
Bildiri Başlığı: Ozkan, E.; Bakar Ates, F. Brassinin Synergistically Induced Anticancer Effects of Imatinib in SW480 Colon Cancer Cells.

 TBS International Biochemistry Congress (2018) – Turkey
Bildiri Başlığı: Bakar Ates, F.; Ozkan, E.; Sengel Turk, C.T. Anticancer effect of cucurbitacin b loaded hybrid nanocarriers on human breast cancer cells.

 HDIR-5, “Translating Science to Medicine:Targets and Therapeutics (2018)- Zagreb, Croatia
Bildiri Başlığı: Bakar Ates, F.; Ozkan, E.; Sengel Turk, C.T. Cucurbitacin B Loaded Lipid Polymer Hybrid Nanocarriers Induced a Significant Decrease in Mitochondrial Membrane Potential in Breast Cancer Cells.

 Congress of the Croatian Society of Biochemistry and Molecular Biology (HDBMB 2019)- Croatia
Bildiri Başlığı: Bakar-Ates, F.; Ozkan, E. The Apoptotic Effect of Atorvastatin in MDAMB231 cells is related with down-regulation of MMP-2/9 mRNA Expression.

 The 7th Drug Chemistry Conference (2019)-Turkey
Bildiri Başlığı: Bakar-Ates, F.; Ozkan, E.; Sengel-Turk, C.T. Effects of Cucurbitacin B Hybrid Nanocarriers on Apoptosis of MDAMB231 Cells Through PARP Cleavage.

 10th International Symposium on Computational Methods in Toxicology and Pharmacology Integrating Internet Resources (CMTPI)-Ioannina, Greece, 23-27 June, 2019.
Bildiri Başlığı: Bozdag-Dundar O., Yüceilyas I., Ozkan E., Bakar-Ates F. Synthesis of some novel flavonyl sulfamoyl quinozalinone compounds as anticancer agents.


Poster Bildiriler:
 The 2nd International Gazi Pharma Symposium Series (GPSS 2017) -Ankara
Poster Başlığı: Ozkan E, Ozmen N, Bakar F. The effects of Lonidamine and Quercetin combination on cell growth and apoptosis of MCF-7 breast cancer cells.

 The 43rd FEBS Congress (2018) – Prague / Czech Republic
Poster Başlığı: Ozkan E, BakarAtes F. The Dose-Dependent Effects Of Brassinin On Apoptosis In SW480 Colorectal Cancer Cells Through MMP-9 Related Pathway.

Gazi University 2002 Gazi University Gazi University

Previous Positions

Research Areas

Selected Publications / All Publications

Uluslararası hakemli dergilerde yayımlanan makaleler:
Zarre, S., Podlech, D., Taeb, F. (2005). New species of genus Astragalus L. (Fabaceae), mainly from the Flora Iranica area. Feddes Repertorium 116(1-2): 54-79.Özüdoğru, B.,
Taeb, F., Zarre, S., Podlech, P., Tillich, H.J., Kazempour Osaloo S., Maassoumi, A.A. (2007). A contribution to the phylogeny of annual species of Astragalus (Fabaceae) in the Old World using hair micromorphology and other morphological characters. Feddes Repertorium 118(5-6): 206-227.
Özüdoğru, B., Erik, S., Taeb, F. (2011). Astragalus pseudopinetorum (Fabaceae) a new species from Turkey. Ann. Bot. Fennici 48: 84-86.
Taeb, F., Uzunhisarcıklı, M.E. (2012). Astragalus argentophyllus (Fabaceae), a new species from south Anatolia, Turkey. Ann. Bot. Fennici 49: 259-262.
Taeb, F., Ekici, M., Podlech, D. (2012). Taxonomic revision of annual species of Astragalus L. (Fabaceae) in Turkey. Feddes Repertorium 123(1): 1-26.

Bilimsel toplantılarda sunulan ve bildiri kitaplarında (proceedings) basılan bildiriler:
Taeb, F., Zarre, S, Maassoumi, A.A., Ghahreman. A. (2004). A Contribution to Systematics of Annual Species of Astragalus (Fabaceae) in the Old World. 12th Congress of Biology, 20-22 Agust, Hamedan University, Iran.
Taeb, F., Zarre, S., Podlech, D., Tillich, H.J., Kazempour Osaloo, S., Maassoumi, A.A. (2005). A contribution to the systemarics of annual species of Astragalus (Fabaceae) in the Old World. XVII International Botanical Congress, 17-23 July 2005, Vienna.
Taeb, F., Maassoumi, A.A., Podlech, D., Ghahreman, A. (2005). A Contribution to Phylogeny of Annual Species of Astragalus (Fabaceae) in the Old World. 14th and first International Congress of Biology, 23-25 Agus. Guilan University, Iran.
Taeb, F., Zarre, S., Maassoumi, A.A., Kazempour Osaloo, S. (2006). Heterogeneity and polyphyly of Astragalus sect. Sesamei (Fabaceae) based on morphological and biogeographical evidences. First National Congress of Biotechnology and Biocatalists, 20-21 November, Azad University, Iran.
Taeb, F., Zarre, S., Maassoumi, A.A., Kazempour Osaloo, S. (2007). Evidences on polyphyly of Astragalus sect. Annulres (Fabaceae). 1th National Congress of Plant Taxonomy, 6 September, Research Institute of Forests and Rangelands, Tehran, Iran.
Taeb, F. Dönmez, A.A., Zarre. S. (2009). Notes on Annual species of Astragalus (Fabaceae) in Turkey. The 80th anniversary of Turrill’s “PLANT LIFE OF THE BALKAN PENINSULA” (5th Balkan Botanical Congress). 7-11th September, Belgrad, Serbia.
Taeb, F., Ekici, M., Podlech, D. (2011). Notes on Astragalus suberosus species complex in Turkey.7 th International Congress of Systematic and Evolutionary. Biology (ICSEB VII)“BIOSYSTEMATICS BERLIN”. 21-27th February, Berlin, Germany
Taeb, F., Zarre, S., Maassoumi, A.A., Kazempour Osaloo, S. (2007). Heterogeneity and polyphyly of Astragalus sect. Sesamei (Fabaceae) based on morphological and biogeographical evidences. International Congress Symposium 7th Plant Life of South West Asia (7thPLoSWA), 25-29 June, Eskişehir, Turkey.
Taeb, F., Uzunhisarcıklı, M.E., Ekici, M. (2012). Threat categories of some endemic species of Astragalus sect. Malacothrix (Fabaceae). 2 th Biorare Endemik Plants Congre, Fethiye, Muğla, Turkey.
Ekşi Bona, G., Yılmaz, G., Taeb Dişli, F., Bona, M., Akalın Çiftçi, G. (2024). ANTICANCER ACTIVITY OF CENTAUREA GLASTIFOLIA L. (ASTERACEAE) LEAF EXTRACT ON A549 CELL LINE. 14th International Symposium on Pharmaceutical Sciences (ISOPS). 25-28th June, Ankara, Türkiye.

Anadolu University 2009 Eskisehir Technical University Eskisehir Technical University

Previous Positions

Research Areas

Microbiology

Selected Publications / All Publications

1. Uluslararası hakemli dergilerde yayınlanan makaleler (SCI & SSCI & Arts and Humanities)
- Yılmaz Cankılıç, M., Arık, G. (2016), Analysıs of cyanobacterial diversity of some hot springs in Afyonkarahisar, Turkey. Applied Ecology and Environmental Research, 14(2): 463-484.
- Kıvanç, S. A., Arık, G., Akova Budak, B., Kıvanç, M. (2018), Biofilm forming capacity and antibiotic susceptibility of Staphylococcus spp. with the icaA/icaD/bap genotype isolated from ocular surface of patients with diabetes, Malawi Medical Journal, 30(4): 243-249.
- Er, S., İstanbullu Tosun, A., Arık, G., Kıvanç, M. (2018). Anticandidal activities of lactic acid bacteria isolated from the vagina. Turkish Journal of Medical Science, doi:10.3906/sag-1709-143.
- Kalyoncu, S., Yilmaz, S., Kuyucu, A.Z. et al. Process development for an effective COVID-19 vaccine candidate harboring recombinant SARS-CoV-2 delta plus receptor binding domain produced by Pichia pastoris. Sci Rep 13, 5224 (2023). https://doi.org/10.1038/s41598-023-32021-9
-Oyku Simsekli, Irfan Bilinmis, Sumeyye Celik, Gizem Arık, Abdullah Yucel Baba & Alptug Karakucuk (2023) Advancing biofilm management through nanoformulation strategies: a review of dosage forms and administration routes, Journal of Drug Targeting, DOI: 10.1080/1061186X.2023.2270619

2. Uluslararası diğer hakemli dergilerde yayınlanan makaleler
- Köseoğlu-Tetik, Z., Şanal-Demirci, S., Arık G. (2019). Isolated and identified bacteria from digestive systems of blood- sucking tabanidae (Insecta: Diptera). International Journal of Entomology Research, 4(6):68-73.
-Arık, G., Yılmaz Sarıözlü, N. (2021). Determination of lipase activities of actinomycetes isolates from soil. Biological Diversity and Conservation, 14/3 (2021) 487-492.
-Arik, G., Kivanc, M., & KIRZIOĞLU, Z., (2022). Diversity of aerobic and facultative anaerobic bacteria forming the supragingival biofilm in healthy children. MALAYSIAN JOURNAL OF MICROBIOLOGY , vol.18, no.5, 555-561.

3. Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında (Proceedings) basılan bildiriler
- Arık, G., Yılmaz Sarıözlü, N. (2011), Determining of Antimicrobial Activity of Actinomycetes Isolated from Different Soil Samples The 4th Congress of European Microbiologists (FEMS), Geneva, İsviçre, 26-30 Haziran.
- Arık, G., Yılmaz, M. (2011), Identification of Thermophilic Cyanobacteria Isolates Obtained from AfyonkarahisarCity-TURKEY IV International Conference on Environmental, Industrial and Applied Microbiology BioMicroWorld , Malaga-İspanya, 14-16 Eylül.
- Berikten, D., Hosgün, E. Z., Arik, G., Yilmaz, Y., Bozan, B., Kivanc, M. (2013), Screening of White Rot Fungal Species for Their Capacity to Increase Enzymatic Hydrolysis of Hazelnut Shell, V. International Conference Environmental, Industrial and Applied Microbiology, Madrid, İspanya 2-4 Ekim.
- Arık, G., Kıvanç, M. (2015), In vitro investigation of biofilm formation capacity of oral lactic acid bacteria isolates on different carbonhydrates, World Congress on Beneficial Microbes: Food, Pharma, Aqua & Beverages Industry Valensiya, İspanya.
- Arık, G., Kıvanç, M. (2019), Oral laktik asit bakterilerinin antioksidan aktivitelerinin belirlenmesi, 2. Uluslararası Sağlık Bilimleri ve Yaşam Kongresi, Burdur, Türkiye 24-27 Nisan.

4. Yazılan uluslararası kitaplar veya kitaplarda bölümler
- Berikten, D., Hoşgün E. Z., Arık, G., Yılmaz, Y., Bozan B., Kıvanç, M. (2014). Screening of White Rot Fungal Species for Their Capacity to Increase Enzymatic Hydrolysis of Hazelnut Shell. Industrial, Medical and Environmental Applications of Microorganisms. Current Status and Trends, A. Mendez-Vilas, Editör, Wageningen Academis Publishers, ss.630-634.

5. Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler
Berikten, D., Hoşgün, E. Z., Arık, G., Bozan, B., Kivanç, M. (2014). Bazı Mikrofungus Türlerinin Selülaz ve Ksilanaz Aktivitelerinin Araştırılması, 22. Ulusal Biyoloji Kongresi, Eskişehir, 23-27 Haziran (poster sunumu).

6. Diğer yayınlar
- Arık, G. Bakteri Destekli Biyomürekkep Üretimi. (2020). Medikal İnovatif Teknolojiler, Arslantaş, A., Aydın H. E., Editör. Eskişehir Osmangazi Üniversitesi Yayınları, ss. 33-42

7. Ulusal & Uluslararası Projeler
Afyon ve Kütahya bölgesindeki bazı termal kaynakların sianobakteri biyoçeşitliliğinin belirlenmesi. BAP-Genel Amaçlı Projeler-Proje Numarası: 1002F85- Araştırmacı (Tamamlandı)
Aktinomiset Kaynaklı Lipaz Geninin Klonlanması, Dizilenmesi ve Ekspresyonu. BAP-Yüksek Lisans Tez Projesi-1005F114-Araştırmacı (Tamamlandı)
Oral Laktik Asit Bakterilerinin Biyofilm ve Halitosis Üzerine Etkilerinin İn Vitro Araştırılması. BAP-Doktora Tez Projesi-Proje Numarası: 1408F371- Araştırmacı (Tamamlandı)
Üst çene bölgesinde mini vida destekli ortodontik apareyler ile yapılan tedaviler sonrasında çıkarılan mini vidaların mikrobiyolojik olarak değerlendirilmesi. BAP-Genel Amaçlı Projeler-Proje Numarası: 1710F535-Araştırmacı (Tamamlandı)
SARS-CoV-2’ye Karşı Rekombinant Protein Temelli Aşı Geliştirilmesi-TÜBİTAK-2247-C STAR Stajyer Araştırmacı Burs Programı-Doktora Sonrası Araştırmacı

Previous Positions

Research Areas

Selected Publications / All Publications

2017

Previous Positions

Research Areas

Biotechnology, Nanoflower, Plant extract, Protein Isolation, Phytotherapy, Tyrosinase enzyme inhibition, Hyaluronidase enzyme inhibition, Sunscreen activity, Antioxidant activity

Selected Publications / All Publications

Uluslararası hakemli dergilerde yayımlanan makaleler:
ONBAŞLI DİLŞAD, YUVALI GÖKÇEN, DURBİLMEZ GÖKŞEN DİLŞAT, ÖÇSOY İSMAİL (2022).
Kitosan-gümüş nanopartikülü ve kitosan-gümüş-grafen oksit nanokompozitinin sentezi,
karakterizasyonu ve antimikrobiyal aktivitelerinin belirlenmesi. Erciyes Üniversitesi Veteriner
Fakültesi Dergisi (Yayın No: 7785267)
Bor Emrah, KOCA ÇALIŞKAN UFUK, ANLAŞ FATMA CEREN, DURBİLMEZ GÖKŞEN DİLŞAT, BAKIREL
TÜLAY, ÖZDEMİR NALAN (2022). Synthesis of Persea americana extract based hybrid nanoflowers
as a new strategy to enhance hyaluronidase and gelatinase inhibitory activity and the evaluation of
their toxicity potential. Inorganic and Nano-Metal Chemistry, Doi:
10.1080/24701556.2022.2072342 (Yayın No: 7714459)
Özdoğan Ayça, KOCA ÇALIŞKAN UFUK, DURBİLMEZ GÖKŞEN DİLŞAT, Küçük Şebnem (2021). Silk
protein fibroin and its applications in health. Acta biologica turcica (Yayın No: 7780337)

Uluslararası hakemli dergilerde yayımlanan makaleler:
DURBİLMEZ GÖKŞEN DİLŞAT, MANCAK KARAKUŞ METHİYE, KOCA ÇALIŞKAN UFUK (2021).
Phytotherapeutic Options in Thyroid Function Disorders. Journal of Traditional Medical
Complementary Therapies (Yayın No: 7785082)
KOCA ÇALIŞKAN UFUK, DURBİLMEZ GÖKŞEN DİLŞAT, Memiş Gökmen (2019). EFFECTS OF
PHYTOTERAPEUTICS ON BENIGN PROSTATE HYPERPLASIA. Journal of Faculty of Pharmacy of
Ankara University (Yayın No: 7785060)
B. Uluslararası bilimsel toplantılarda sunulan ve bildiri kitaplarında (proceedings)
basılan bildiriler :
ONBAŞLI DİLŞAD, DURBİLMEZ GÖKŞEN DİLŞAT, YUVALI GÖKÇEN, ÖÇSOY İSMAİL, Fidan Sercan
(2017). Kitosan-gu?mu?ş ve kitosan-gu?mu?ş-grafen oksit nanopartiku?llerinin sentezlenmesi ve
antimikrobiyal aktivitelerinin belirlenmesi. İVEK 3. İnternational Convention of Pharmaceuticalsn
and Pharmacies (Özet Bildiri/Poster)(Yayın No:7785235)
DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2019). Kronik obstru?ktif akcig?er
hastalıg?ı (KOAH) Tedavisinde tıbbi bitkilerin rolu?,. ITCM-2 (2. İnternational Traditional And
Complementary Medicine Congress) (Özet Bildiri/Poster)(Yayın No:7785210)
DURBİLMEZ GÖKŞEN DİLŞAT, Bor Emrah, DÖNMEZ CEYLAN, GEÇİLİ FİRDEVS, ÖZDEMİR NALAN,
KOCA ÇALIŞKAN UFUK (2019). Synthesis of Hybrid Nanoflowers with Plant Extracts Traditionally
Utilized In Skin Problems and Their Activity Profile. I. International Aromatic Plants and Cosmetic
Symposium (Tam Metin Bildiri/Sözlü Sunum)(Yayın No:7785134)
DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2020). Synthesis and characterization of
silk protein and sericin nanoflowers, Poster Sunumu. IPPC (Özet Bildiri/Poster)(Yayın
No:7785200)
DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2021). Investıgatıon of hyaluronıdase
ınhıbıtıon of copper and zınc nanoflowers of methanol extract of cotınus coggygrıa plant. In 10th
International Phytocosmetics and Phytotherapy Congress (IPPC GREECE) (Özet Bildiri/Sözlü
Sunum)(Yayın No:7785156)
DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2021). Isolition of silk protein and
synthesis/ characterization hybrid nanoflowers. GPSS (Özet Bildiri/Sözlü Sunum)(Yayın
No:7785141)
DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2021). Comparatıve study of
antıhyaluronıdase actıvıtıes of hybrıd nanoflowers of rosmarınus offıcınalıs methanol plant extract.
13th International Symposium on Pharmaceutical Sciences (ISOPS-13), (Özet Bildiri/Sözlü
Sunum)(Yayın No:7785150)
DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2022). Investigation of hyaluronidase
enzyme Inhibition of natural fatty oIls and evaluation of the results In terms of derma products.
In International Phytocosmetics and Phytotherapy Congress (IPPC Egypt), (Özet Bildiri/Sözlü
Sunum)(Yayın No:7785164)
DURBİLMEZ GÖKŞEN DİLŞAT, ERDÖNMEZ DEMET, KOCA ÇALIŞKAN UFUK (2023). Anti-quorum sensıng and antımicrobial activity of zinc
and copper nanoflowers derived from Cotinus coggygria and Rosmarinus oficınalis plant species.The 9th International Mediterranean Symposium on Medicinal and Aromatic Plants, (Özet Bildiri/Sözlü
Sunum)(Yayın No:ISBN: 978-625-00-1361-8)

C. Yazılan ulusal/uluslararası kitaplar veya kitaplardaki bölümler:
C2. Yazılan ulusal/uluslararası kitaplardaki bölümler:
Advances in Phytopharmaceuticals for Human Health Apple Academic Press, Bölüm
adı:(Hyaluronıdase and gelatinase (MMP-2, MMP-9) inhibitör plants) (2022)., DÖNMEZ CEYLAN,
DURBİLMEZ GÖKŞEN DİLŞAT, SEEDi H. EL, KOCA ÇALIŞKAN UFUK, Apple acedemic press,
Basım sayısı:1, Sayfa Sayısı 257, ISBN:978-1-77188-857-8, Türkçe(Bilimsel Kitap), (Yayın No:
7785108)
E. Ulusal bilimsel toplantılarda sunulan ve bildiri kitaplarında basılan bildiriler:
DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2018). Doğal Ergojenikler ve Spor Eczacılığında
Eczacının ve Akademisyenin Rolü. BİHAT-23 (23. Bitkisel İlac? Hammaddeleri Toplantısı), (Özet
Bildiri/Poster)(Yayın No:7785189)
KOCA ÇALIŞKAN UFUK, DURBİLMEZ GÖKŞEN DİLŞAT (2018). Phytotherapeutics in sports exercises.
ITCM-1 (1. İnternational Traditional And Complementary Medicine Congress) (Özet Bildiri/Poster)(Yayın
No:7785222)
Yıldırım Selda, DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2019). Cannabis Use in Skin
Disorders and Cosmeceutical Products. I. International Aromatic Plants and Cosmetic Symposium
(Tam Metin Bildiri/Sözlü Sunum)(Yayın No:7785117)
DURBİLMEZ GÖKŞEN DİLŞAT, KOCA ÇALIŞKAN UFUK (2022). Bombyx Mori Kozalarından Protein
İzolasyonu, Hibrit Nanoçiçeklerin Sentezi, Karakterizasyonu ve In Vitro Deneylerle Karşılaştırmalı
Olarak Analizi. 24. BİHAT (Özet Bildiri/Sözlü Sunum)(Yayın No:7785193)

Ankara University Ankara University, Faculty of Pharmacy Ankara University, Faculty of Pharmacy

Previous Positions

Lokman Hekim University, Faculty of Medicine

Research Areas

Pharmacology, Medical Pharmacology, Molecular Pharmaclogy, In vivo preclinical studies, In vitro preclinical studies, Experimental animal studies, Erectile dysfunction, Vascular damage, Cardiovascular diseases, Urogenital system diseases.

Selected Publications / All Publications

Uluslararası hakemli dergilerde yayımlanan makaleler:

Asker, H; Yilmaz-Oral, D; Oztekin CV; Gur,S, “An Update On The Current Status and Future Prospects Of Erectile Dysfunction Following Radical Prostatectomy“, Prostate, 82(12):1135-1161; 2022 Sep; Epub 2022 May 17; doi: 10.1002/pros.24366.

Yilmaz-Oral, D; Kaya-Sezginer, E; Asker, H; Gur,S; "Co-Administration Of Sodium Hydrosulfide And Tadalafil Modulates Hypoxia And Oxidative Stress On Bladder Dysfunction In A Rat Model Of Bladder Outlet Obstruction", Int Braz J Urol., 48(6):971-980; 2022 Nov-Dec; doi: 10.1590/S1677-5538.IBJU.2022.0207.

Korkmaz, F; Yilmaz-Oral, D; Asker, H; Guven, B; Turkcan, D; Kirlangic, OF; Oztekin, CV; Gur, S, "Combined Levothyroxine and Testosterone Treatment For Restoring Erectile Dysfunction In Propylthiouracil-Induced Hypothyroid Rats", The Journal of Sexual Medicine, 00, 1–10; 2023 Apr; doi: org/10.1093/jsxmed/qdad034.

Yilmaz-Oral, D; Sezen, SF; Turkcan, D; Asker, H; Kaya-Sezginer, E; Kirlangic, OF; Elçi, MP; MOzen, FZ; Gur,S, "Dual Strategy with Adipose-derived Stem Cells and L-arginine Recovered Cavernosal Functions in a Rat Model of Radical Prostatectomy", Stem cells and development, 33(1-2):43-53; Epub 2024 Jan 10; doi:10.1089/scd.2023.0178.

Uluslararası bilimsel toplantılarda sunulan ve bildiri kitaplarında (proceedings) basılan bildiriler:

‘Recovery of Erectile Dysfunction After Administration of Hydrogen Sulfide Donor Sodium Hydrogen Sulfide and Transplantation of Adipose-Derived Stem Cells in Rats With Bilateral Cavernous Nerve İnjury’
Asker, H; Sezen, SF; Yilmaz-Oral, D; Turkcan, D; Elçi, MP; Kirlangic, OF; Gur, S,
22nd world meeting of the international society of sexual medicine November 19-21, 2021 virtual

‘Dual Strategy with Intracavernosal Implantation of Adipose-derived Stem Cells and Daily Oral L-arginine Optimize Recovery of and Cavernosal Functions after Cavernous Nerve Injury in Rats’
Yilmaz-Oral, D; Sezen, SF; Turkcan, D; Asker, H; Kaya-Sezginer, E; Kirlangic, OF; Elçi, MP; MOzen, FZ; Gur, S, 22nd ANNUAL FALL SCIENTIFIC MEETING OF SMSN October 21-24, 2021 The Westin Kierland,Scottsdale, AZ, USA.

‘Treatment with levothyroxine and testosterone ameliorated erectile dysfunction in rat model of propylthiouracilinduced hypothyroidism’,
Korkmaz, F; Yilmaz-Oral, D; Asker, H; Guven, B; Turkcan, D; Kirlangic, OF; Oztekin, CV; Gur, S, 22nd ANNUAL FALL SCİENTİFİC MEETİNG OF SMSN October 21-24 2021 The Westin Kierland,Scottsdale, AZ, USA.

Bilkent University 2006 University of Rochester University of Rochester

Previous Positions

University of Michigan Medical School, Ann Arbor, MI-USA (2012-2018)

Elixir Pharmaceutical R&D Corporation, Ankara, TURKEY (2019-2020)

Research Areas

Protein biochemistry, bioinorganic chemistry (metalloproteins), enzymology, analytical chemistry (for generic drug development), biotechnology, spectroscopy, chromatography, and structural biology.

Selected Publications / All Publications

Wiley, S., Griffith, C., Eckert, P., Mueller, A. P., Nogle, R., Simpson, S. D., Köpke, M., Can, M., Sarangi, R., Kubarych, K., Ragsdale, S. W. (2024). An Alcove at the Acetyl-CoA Synthase Nickel Active Site is Required for Productive Substrate CO Binding and Anaerobic Carbon Fixation. Journal of Biological Chemistry, 300 (8), 107503.
https://doi.org/10.1016/j.jbc.2024.107503

Can, M., Abernathy, M. J., Wiley, S., Griffith, C., James, C. D., Xiong, J., Guo, Y., Hoffman, B. M., Ragsdale, S. W., Sarangi, R. (2023). Characterization of Methyl- and Acetyl-Ni Intermediates in Acetyl CoA Synthase Formed during Anaerobic CO2 and CO Fixation. Journal of the American Chemical Society, 145(25), 13696–13708. https://doi.org/10.1021/jacs.3c01772

Cohen, S. E., Brignole, E. J., Wittenborn, E. C., Can, M., Thompson, S., Ragsdale, S. W., Drennan, C. L. (2021). Negative-Stain Electron Microscopy Reveals Dramatic Structural Rearrangements in Ni-Fe-S-dependent Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase. Structure, 29(1), 43-49.
https://doi.org/10.1016/j.str.2020.08.011

Cohen, E. S., Can, M., Wittenborn, E. C., Hendrickson, R. A., Ragsdale, S. W., Drennan, C. L. (2020). Crystallographic
Characterization of the Carbonylated A-cluster in Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase. ACS Catalysis, 10(17), 9741–9746. https://doi.org/10.1021/acscatal.0c03033

Chen, P. Y.-T., Aman, H., Can, M., Ragsdale, S. W., & Drennan, C. L. (2018). Binding Site for Coenzyme A Revealed in the Structure of Pyruvate:Ferredoxin Oxidoreductase from Moorella Thermoacetica. Proceedings of the National Academy of Sciences of the USA, 115(15), 3846-3851. https://doi.org/10.1073/pnas.1722329115

Burton, R., Can, M., Esckilsen, D., Wiley, S., & Ragsdale, S. W. (2018). Production and Properties of Enzymes that Activate and Produce Carbon Monoxide. Methods in Enzymology, 613, 297–324.
https://doi.org/10.1016/bs.mie.2018.10.005

Zhang, L., Can, M., Ragsdale, S. W., & Armstrong, F. A. (2018). Fast and Selective Photoreduction of CO2 to CO
Catalyzed by a Complex of Carbon Monoxide Dehydrogenase, TiO2, and Ag Nanoclusters. ACS Catalysis, 8(4), 2789–2795. https://doi.org/10.1021/acscatal.7b04308

Pierce, E., Mansoorabadi, S. O., Can, M., Reed, G. H., & Ragsdale, S. W. (2017). Properties of Intermediates in the Catalytic Cycle of Oxalate Oxidoreductase and Its Suicide Inactivation by Pyruvate. Biochemistry, 56(22), 2824–2835. https://doi.org/10.1021/acs.biochem.7b00222

Can, M., Giles, L. J., Ragsdale, S. W., & Sarangi, R. (2017). X-ray Absorption Spectroscopy Reveals an
Organometallic Ni–C Bond in the CO-Treated Form of Acetyl-CoA Synthase. Biochemistry, 56(9), 1248–1260.
https://doi.org/10.1021/acs.biochem.6b00983

Gibson, M. I., Chen, P. Y.-T., Johnson, A. C., Pierce, E., Can, M., Ragsdale, S. W., & Drennan, C. L. (2016). One-Carbon Chemistry of Oxalate Oxidoreductase Captured by X-ray Crystallography. Proceedings of the National Academy of Sciences of the USA, 113(2), 320–325. https://doi.org/10.1073/pnas.1518537113

Wang, V. C.-C., Islam, S. T. A., Can, M., Ragsdale, S. W., & Armstrong, F. A. (2015). Investigations by Protein Film
Electrochemistry of Alternative Reactions of Nickel-Containing Carbon Monoxide Dehydrogenase. The Journal of Physical Chemistry B, 119(43), 13690–13697. https://doi.org/10.1021/acs.jpcb.5b03098

Gibson, M. I., Brignole, E. J., Pierce, E., Can, M., Ragsdale, S. W., & Drennan, C. L. (2015). The Structure of an Oxalate Oxidoreductase Provides Insight into Microbial 2-Oxoacid Metabolism. Biochemistry, 54(26), 4112–4120.
https://doi.org/10.1021/acs.biochem.5b00521

Can, M., Armstrong, F. A., & Ragsdale, S. W. (2014). Structure, Function, and Mechanism of the Nickel
Metalloenzymes, CO Dehydrogenase, and Acetyl-CoA Synthase. Chemical Reviews, 114(8), 4149–4174.
https://doi.org/10.1021/cr400461p

Bachmeier, A., Wang, V. C. C., Woolerton, T. W., Bell, S., Fontecilla-Camps, J. C., Can, M., Ragsdale, S. W., Chaudhary, Y. S., & Armstrong, F. A. (2013). How Light-Harvesting Semiconductors Can Alter the Bias of Reversible Electrocatalysts in Favor of H2 Production and CO2 Reduction. Journal of the American Chemical Society, 135(40), 15026–15032. https://doi.org/10.1021/ja4042675

Wang, V. C.-C., Can, M., Pierce, E., Ragsdale, S. W., & Armstrong, F. A. (2013). A Unified Electrocatalytic
Description of the Action of Inhibitors of Nickel Carbon Monoxide Dehydrogenase. Journal of the American
Chemical Society, 135(6), 2198–2206. https://doi.org/10.1021/ja308493k

Can, M., Krucinska, J., Zoppellaro, G., Andersen, N. H., Wedekind, J. E., Hersleth, H.-P., Andersson, K. K., & Bren, K. L. (2013). Structural Characterization of Nitrosomonas europaea Cytochromec-552 Variants with Marked Differences in Electronic Structure. ChemBioChem, 14(14), 1828–1838. https://doi.org/10.1002/cbic.201300118

Ando, N., Kung, Y., Can, M., Bender, G., Ragsdale, S. W., & Drennan, C. L. (2012). Transient B12-Dependent
Methyltransferase Complexes Revealed by Small-Angle X-ray Scattering. Journal of the American Chemical Society,
134(43), 17945–17954. https://doi.org/10.1021/ja3055782

Levin, B. D., Can, M., Bowman, S. E. J., Bren, K. L., & Elliott, S. J. (2011). Methionine Ligand Lability in Bacterial
Monoheme Cytochromes c: An Electrochemical Study. The Journal of Physical Chemistry B, 115(40),
11718–11726. https://doi.org/10.1021/jp203292h

Can, M., Zoppellaro, G., Andersson, K. K., & Bren, K. L. (2011). Modulation of Ligand-Field Parameters by Heme
Ruffling in Cytochromes c Revealed by EPR Spectroscopy. Inorganic Chemistry, 50(23), 12018–12024.
https://doi.org/10.1021/ic201479q

Hacettepe University Faculty of Pharmacy; Kırıkkale University Faculty of Law 2013 (Eczacılık Fakültesi); 2020 (Hukuk Fakültesi) Hacettepe University Faculty of Pharmacy Hacettepe University Faculty of Pharmacy

Previous Positions

Hacettepe University Faculty of Pharmacy

Research Areas

Pharmacy, pharmacognosy, folk medicine, phytochemistry, natural compounds, bioactive metabolites, cell culture studies; health law, pharmaceutical law

Selected Publications / All Publications

Taştekin NH, Atakay M, Salih B, Başaran AA. 2022. Isolation and Characterization of Rare Flavone Tetraglycosides from the Seeds of the Bioactive Plant: Peganum harmala L. Analytical Letters, 1-12, doi: 10.1080/00032719.2022.2135722

Taştekin NH, Özenver N. 2023. Cordyceps militaris (L.): Medicinal Aspects in Terms of Ethnobotanical and Pharmacological Perspectives. Agrawal DC, Dhanasekaran M, editors. Mushrooms with Therapeutic Potentials Recent Advances in Research and Development. Singapore: Springer; 345-368.

2011

Previous Positions

Research Areas

Selected Publications / All Publications

A. Uluslararası hakemli (SCI) dergilerde yayımlanan makaleler:

A.1 Akay Sazaklioglu, S., Torul, H., Kabadayi, H., Vatansever, H. S., Tamer, U., Celikkan, H. Calibration Curve Approaches for Nonlinear Data Points Obtained in Colo 320 Exosomes Determination. Analytical and Bioanalytical Electrochemistry, 2022; 14(11): 1027-1043.

A.2 Sazaklıoğlu, S.A., Torul, H., Vatansever, H.S. Tamer, U., Çelikkan, H. Direct impedimetric detection of exosomes and practical application in urine. J Appl Electrochem (2022). https://doi.org/10.1007/s10800-022-01753-3

A.3 Sevda Akay, Burak Esat, Daria Vladikova, Ivaylo Genov, Emiliya Mladenova, “A Novel Proton Conducting Polymer Functionalized with 1-Hydroxy-Benzimidazole-3-oxide”, International Journal of Hydrogen Energy. 41 (2016) 12101-12107.

B. Uluslararası bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler:

B.1 Çalık Kayiş, E., Torul, H., Akay Sazaklioglu, S., Celikkan, H., Vatansever, H. S., & Tamer, U., (2023). SERS based exosome detection using paper substrates. 33rd International Symposium on Pharmaceutical and Biomedical Analysis (PBA 2023) (pp.1). Ankara, Turkey

B.2 Akay Sazaklıoğlu S., Torul H., Vatansever H. S. , Tamer U., Çelikkan H. Label-Free Determination of Extracellular Vesicles onto Gold Screen Printed Electrodes by Electrochemical Impedance Spectroscopy, 4th International Congress on Analytical and Bioanalytical Chemistry, TURKEY, 23 March 2022

B.3 Sevda Akay Sazaklıoglu, Hilal Torul, Hilal Kabadayı, Hüseyin Çelikkan, Seda Vatansever, Uğur Tamer, "Determination of Colo 320 Extracellular Vesicles via Gold Electrode and Calibration Curve Study for High Concentration Sample", International Eurasian Conference on Biotechnology and Biochemistry, 16-18 December 2020, Ankara/Turkey.

B.4 Sevda Akay, Ivaylo Genov, Emiliya Mladenova, Burak Esat, Daria Vladikova, “10th International Symposium on Electrochemical Impedance Analysis Proton Conductivity Studies of Novel Organic Polymers, Borovetz-Rila Mountain, Bulgaria. June 1-5, 2014.

B.5 S Akay, B Esat, I Fidan, C Hirel, N Frank, "New Benzimidazole Nitronyl Nitroxides As Electro-Active Compounds for Battery Electrodes" ECS Meeting Abstracts, 2014-04 391.

B.6 Burak Esat, Sumeyye Bahceci, Muhammed Aydin, Sevda Akay, "224th ECS Meeting, (October 27 - November 1, 2013) Batteries, Fuel Cells, and Energy Conversion", San Francisco, California, USA, Oct. 2013.

B.7 Sümeyye Bahçeci, Sevda Akay, Muhammed Aydın, Burak Esat, "5th International Conference on Advanced Lithium Batteries for Automobile Applications", Istanbul Technical University, Istanbul/Turkey, Sep. 2012.

C. Ulusal bilimsel toplantılarda sunulan ve bildiri kitabında basılan bildiriler:

C.1 Akay Sazaklıoğlu S., Torul H., Kabadayı H., Vatansever H. S. , Tamer U., Çelikkan H. Eksozomların Kağıt Tabanlı Elektrotlar Kullanılarak İmpedimetrik Tayini, 10. Ulusal Analitik Kimya Kongresi, Muğla, Turkey, 7 - 11 Eylül 2022, pp.135

PROJELER

1. Polimer Elektrot Malzemesi ve Polimer Elektrolit Geliştirilmesi ve Değişik Tip Pillerdeki Uygulamaları, TUBITAK (2013-2014), 112T516 (Bursiyer)

2. Organik Elektro-Aktif Gruplarla Fonksiyonellendirilmiş Grafen Malzemeler ve Güç Depolama Sistemlerindeki Uygulamaları, TUBITAK (2014-2015), 114Z295 (Bursiyer)

3. Modifiye Substratlar Kullanılarak Prostat Kanseri Eksozomlarının Yüzeyde Zenginleştirilmiş Raman Spektroskopisi (YZRS) ve Elektrokimyasal İmpedans Spektroskopisi (EIS) ile Tayini, Gazi Üniversitesi BAP, FCD-2021-7119, (2021-2023) (Araştırmacı)

ÖDÜLLER:
• Best Presentation as a Young Scientist - 10th International Symposium on Electrochemical Impedance Analysis, 2014, Borovets- Rila Mountain, Bulgaria.

Ankara University 2006-2011 Gazi University Faculty of Medicine Gazi University Faculty of Medicine

Previous Positions

Post Doc- Researcher- Department of Chemistry, Middle East Technical University, Ankara-Turkey

Research Areas

Molecular and Experimental Pharmacology-Molecular Mechanisms of Pharmacological Action of Phytochemicals and Synthetic Molecules, in vitro or in vivo-Preclinical Toxicology- Redox Homeostasis in metabolic disorders (Diabetes) and neurodegenerative diseases ( Alzheimer, Parkinson) and potential therapeutic approaches to link or overcome their relationships- Neuroinflammation- Photodynamic therapy

Selected Publications / All Publications

Almammadov, T., Elmazoglu, Z., Atakan, G., Kepil, D., Aykent, G., Kolemen, S., & Gunbas, G. (2022). Locked and Loaded: β-Galactosidase Activated Photodynamic Therapy Agent Enables Selective Imaging and Targeted Treatment of Glioblastoma Multiforme Cancer Cells. ACS Applied Bio Materials, 5(9), 4284-4293

Kilic, E., Elmazoglu, Z., Almammadov, T., Kepil, D., Etienne, T., Marion, A., Gunbas, G., & Kolemen, S. (2022). Activity-Based Photosensitizers with Optimized Triplet State Characteristics Toward Cancer Cell Selective and Image Guided Photodynamic Therapy. ACS Applied Biomaterials, 5(6), 2754–2767.

Elmazoglu, Z., Kayhan, H., Santamaría, A., Rangel-López, E., Uğur, P. K., Ceylan, A., Aschner, M., & Karasu, Ç. (2021). Platinum nanoparticles Protect Against Lipopolysaccharide-Induced Inflammation in Microglial BV-2 Cells via Decreased Oxidative Damage and Increased Phagocytosis. Neurochemical Research, 46(12), 3325–3341.

Elmazoglu, Z., Aydın Bek, Z., Saribas, S. G., Özoğul, C., Goker, B., Bitik, B., Aktekin, C. N., & Karasu, Ç. (2021). S-Allylcysteine Inhibits Chondrocyte Inflammation to Reduce Human Osteoarthritis via Targeting RAGE, TLR4, JNK and Nrf2 Signaling: Comparison with Colchicine. Biochemistry and cell biology = Biochimie et biologie cellulaire, 10.1139/bcb-2021-0004.

Elmazoglu, Z., Prnova, M. S., Stefek, M., Ceylan, A. F., Aschner, M., Rangel-López, E., Santamaria, A., & Karasu, C. (2021). Protective Effects of Novel Substituted Triazinoindole Inhibitors of Aldose Reductase and Epalrestat in Neuron-like PC12 Cells and BV2 Rodent Microglial Cells Exposed to Toxic Models of Oxidative Stress: Comparison with the Pyridoindole Antioxidant Stobadine. Neurotoxicity Research, 10.1007/s12640-021-00349-7.

Elmazoglu, Z., Galván-Arzate, S., Aschner, M., Rangel-López, E., Bayraktar, O., Santamaría, A., & Karasu, Ç. (2021). Redox-active phytoconstituents ameliorate cell damage and inflammation in rat hippocampal neurons exposed to hyperglycemia+Aβ1-42 peptide. Neurochemistry International, 145, 104993.

Elmazoglu, Z., Prnova, M. S., Santamaria, A., Stefek, M., & Karasu, C. (2021). Combatting Nitrosative Stress and Inflammation with Novel Substituted Triazinoindole Inhibitors of Aldose Reductase in PC12 Cells Exposed to 6-Hydroxydopamine Plus High Glucose. Neurotoxicity Research, 39(2), 210–226.

Elmazoglu, Z., Bek, Z. A., Sarıbaş, G. S., Özoğul, C., Goker, B., Bitik, B., Aktekin, C.N., & Karasu, Ç. (2020). TLR4, RAGE, and p‐JNK/JNK mediated inflammatory aggression in osteoarthritic human chondrocytes are counteracted by redox‐sensitive phenolic olive compounds: Comparison with ibuprofen. Journal of Tissue Engineering and Regenerative Medicine, 14: 1841– 1857.

Elmazoglu, Z., Rangel-López, E., Medina-Campos, O. N., Pedraza-Chaverri, J., Túnez, I., Aschner, M., Santamaria, A., & Karasu, Ç. (2020). Cannabinoid-profiled agents improve cell survival via reduction of oxidative stress and inflammation, and Nrf2 activation in a toxic model combining hyperglycemia+ Aβ1-42 peptide in rat hippocampal neurons. Neurochemistry International, 140, 104817.

Marmara University 2021

Previous Positions

Research Areas

Selected Publications / All Publications

Mersin University 2016 Ankara University Graduate School of Health Sciences , Department of Pharmacognosy Ankara University Graduate School of Health Sciences , Department of Pharmacognosy

Previous Positions

Hacettepe Oncology Hospital, Robotic Chemotherapy Drug Preparation Unit Manager (2017-2022)

Research Areas

Pharmacognosy

Selected Publications / All Publications

Previous Positions

Research Areas

Selected Publications / All Publications

Hacettepe University 2019 Hacettepe University Hacettepe University

Previous Positions

Meral Pharmacy
Bolu/Türkiye

Research Areas

Biopharmaceutical and
Pharmacokinetics
Pharmaceutical Technology

Selected Publications / All Publications

Gazi University 2020 Gazi University Gazi University

Previous Positions

Research Areas

Pharmaceutıcal Chemistry
Medicinal Chemistry
Design of Drug Molecules

Selected Publications / All Publications

Poster Bildirileri

Synthesis and Biological Activities of Some Benzazole Derivatives
YILDIRIM N.N., KUYRUKCU-OZTURK O., DUNDAR Y.
DRD’23, International Multidiciplinary Symposium on Drug Reseach and Development ,İzmir, Türkiye, 4-6 Mayıs 2023

Gazi University Gazi University, Faculty of Pharmacy, Department of Pharmacognosy Gazi University, Faculty of Pharmacy, Department of Pharmacognosy

Previous Positions

Research Areas

Pharmacognosy

Selected Publications / All Publications

Küpeli Akkol, E., Karatoprak, G. Ş., Dumlupınar, B., Bahadır Acıkara, Ö., Arıcı, R., Yücel, Ç., Aynal, L. C., & Sobarzo Sánchez, E. (2025). Stilbenes Against Alzheimer’s Disease: A Comprehensive Review of Preclinical Studies of Natural and Synthetic Compounds Combined with the Contributions of Developed Nanodrug Delivery Systems. Molecules, 30(9), 1982. https://doi.org/10.3390/molecules30091982

Biruni University 2021 Biruni University Biruni University

Previous Positions

Istanbul Medipol University

Research Areas

PHARMACEUTICAL TECHNOLOGY

Selected Publications / All Publications

HAZIRLANIYOR

Ihsan Dogramaci Bilkent University 2019 Hacettepe University Pharmacy Department Analytical Chemistry Hacettepe University Pharmacy Department Analytical Chemistry

Previous Positions

Elixir Pharmaceutical Research and Development Corporation

As an Analytical Chemistry Specialist

Research Areas

Analytical Chemistry (Pharmacy), Validation, Inorganic Chemistry, Synthesis and Characterization

Selected Publications / All Publications

Turgut, A.M., Ozer, D., Icten, O. et al. Solvent–Free Oxidation of Benzyl Alcohol Over Mechanochemically Prepared Fe3BO6–CeO2 Catalyst. Catal Lett 153, 1719–1725 (2023). https://doi.org/10.1007/s10562-022-04098-w

Abstract
A series of Fe3BO6–xCeO2 (x = 1, 5, 10, 20% by mole) mixtures was prepared via ball-milling process. The physicochemical properties of the mixtures have been characterized by X-ray diffraction, Fourier Transform Infrared Spectra, Scanning Electron Microscopy, Energy Dispersive X-Ray Spectroscopy, and N2 Adsorption–Desorption techniques. The results showed that CeO2 was well dispersed in the iron borate nano-particulate matrix after grinding. The oxidation of benzyl alcohol was investigated using the prepared catalysts. The reaction was carried out in a stirred reactor under reflux using liquid benzyl alcohol in the presence of hydrogen peroxide oxidant, focusing on the conversion and selectivity towards benzaldehyde. Optimization studies were carried out for the solvent type, temperature, reaction time, benzyl alcohol/catalyst ratio, and catalyst composition parameters. It was observed that conversion increased with CeO2 addition up to a certain molar percentage but decreased again on further addition. 34.3% conversion and 81.5% benzaldehyde selectivity were reached after 4 h of reaction at 90 °C in a solvent-free environment with the catalyst containing 5% CeO2. The catalyst was found to be stable when used under these conditions, and there was a slight decrease in its activity after three recycles.

Previous Positions

Research Areas

Selected Publications / All Publications

Previous Positions

Research Areas

Selected Publications / All Publications

Previous Positions

Research Areas

Selected Publications / All Publications

Previous Positions

Research Areas

Selected Publications / All Publications

Previous Positions

Research Areas

Selected Publications / All Publications

Gazi University 2018

Previous Positions

Research Areas

Pharmaceutical Microbiology, Clinical Microbiology

Selected Publications / All Publications

HACETTEPE UNIVERSITY 2020-2021

Previous Positions

Research Areas

Selected Publications / All Publications

Previous Positions

Research Areas

Selected Publications / All Publications

Previous Positions

Research Areas

Selected Publications / All Publications

2021

Previous Positions

Research Areas

Selected Publications / All Publications

YAYINLAR
Simsekli, O., Bilinmis, I., Celik, S., Arık, G., Baba, A. Y., & Karakucuk, A. (2023). Advancing biofilm management through nanoformulation strategies: a review of dosage forms and administration routes. Journal of Drug Targeting, 31(9), 931-949.
Losada-Barreiro, S., Celik, S., Sezgin-Bayindir, Z., Bravo-Fernández, S., & Bravo-Díaz, C. (2024). Carrier Systems for Advanced Drug Delivery: Improving Drug Solubility/Bioavailability and Administration Routes. Pharmaceutics, 16(7), 852.
POSTER BİLDİRİSİ
Development of Dual-Mediated Liposomal Systems CELIK S.,BAYINDIR Z.S. ISOPS 2024, International Symposium on Pharmaceutical Sciences, Ankara, Türkiye.

Previous Positions

Research Areas

Selected Publications / All Publications

Previous Positions

Research Areas

Selected Publications / All Publications

Fatih University 2011 Necmettin Erbakan University

Previous Positions

Research Areas

Cancer, Tumor Immunology, medical Genetics

Selected Publications / All Publications

F. Seçer Çelik, C. Eroglu Guneş, E. Yavuz, E. Kurar. Apelin triggers macrophage polarization to M2 type in head and neck cancer. Immunobiology. 2023 Mar;228(2):152353.
B. Uyar, NG. Özsamur, F. Secer Celik, I. Özbayram, S. Erbas-Cakmak. Downregulation of gene expression in hypoxic cancer cells by an activatable G-quadruplex stabiliser. Chem Commun (Camb). 2023 Feb 21;59(16):2247-2250.
C. Eroğlu Güneş, F. Seçer Çelik, M. Seçme, L. Elmas, Y. Dodurga, E. Kurar. Glycoside Oleandrin downregulates toll-like receptor pathway genes and associated miRNAs in human melanoma cells. Gene, 2022, 843;146805.
F. Seçer Çelik, E. Çelen, H. K. Yildiz, S. Altweish, H. Dönmez, Y. Gürbüz, A. Demirci, E. Büyük, E. Ün Arslan, M. Ilhan, AS. Şahin, H. Vural. Investigation of Leptin Receptor and eNOS Gene Polymorphisms in Preeclamptic Umbilical Cords, World Journal of Gynecology & Women’s Health, 2018, 2641-6247,1,3,1-5.
F. Seçer Çelik, T. Çora, A. Kalayci Yigin. Investigation of genotoxic and cytotoxic effects of acrylamide in HEK293 cell line. Journal of Cancer Prevention and Current Research, 2018, 2373- 633X,9,5, 260-264.

Previous Positions

Research Areas

Selected Publications / All Publications

University of Delhi 2011 Hacettepe Üniversitesi Hacettepe University

Previous Positions

Jamia Millia Islamia University

Research Areas

Foreign Language Education and Research

Selected Publications / All Publications

1. EFFECTS OF COMPUTER-BASED VISUAL MATERIALS USING TO THE SUCCESS IN
TEACHING TURKISH AS A FOREIGN LANGUAGE, https://oaji.net/articles/2017/515-1488838904.pdf


2. Turkish Language and Turkish Literature Teaching in India and Yunus
Emre Institute, https://johschool.com/?mod=tammetin&makaleadi=&key=51634


3. TÜRKÇENİN YABANCI DİL OLARAK ÖĞRETİMİ, https://www.turcademy.com/tr/kitap/turkcenin-yabanci-dil-olarak-ogretimi-9786058006010,
Pegem Akademi Yayıncılık.


4. Needs Analysis in Turkish Teaching as a Foreign Language and Second Language: India as an Example, http://www.openaccess.hacettepe.edu.tr:8080/xmlui/bitstream/handle/11655/25853/MINHAJ%20MOHD%20tez%2010422097.pdf?sequence=2


5. Evaluating the use of Online Digital Applications by Learners of Turkish as a Foreign Language ,http://dunyadiliturkce2020.gazi.edu.tr/kitap.pdf


6. Hindistan’da Yabancı Dil Olarak Türkçe Öğreniminde Çevrimiçi ve Çevrimdışı Dijital Uygulamaların Kullanımı, VIII. INTERNATIONALCONGRESS OF TEACHING TURKISH AS A FOREIGN LANGUAGE

7. Problems Encountered in Writing Skills of Indian Students in Teaching Turkish as Foreign Language

Gazi University 2017 Hacettepe Üniversitesi Hacettepe University

Previous Positions

Anlara University Research and Application Hospital

Research Areas

Surgical Diseases Nursing, Cardiovascular Surgery, Extracorporeal Membrane Oxygenation Nursing Care

Selected Publications / All Publications

Istanbul University 2017 İstanbul Üniversitesi Istanbul University

Previous Positions

Istanbul Nişantaşı University

Research Areas

History / History of the Republic of Turkey / Ataturk's Principles and Revolution History

Selected Publications / All Publications

"Ekonominin Millileştirilmesi Bağlamında Türklerin İş Gücünü Artırmaya Yönelik Bir Kanun: Türkiye’de Türk Vatandaşlarına Tahsis Edilen San’at ve Hizmetler Hakkında Kanun", Yayın Yeri: VII. Anadolu International Conference on Economics , (31.05.2024 -02.06.2024 )

Previous Positions

Research Areas

Selected Publications / All Publications

Hacettepe University 2004 Ankara Üniversitesi/Sosyal Bilimler Enstitüsü Ankara University/ Social Sciences İnstitute

Previous Positions

Bilkent University / Instructor

Research Areas

Ottoman Turkish, Ottoman Law in Early Modern Era, Gender at Early Modern Era Ottoman Society, Turkish Literature

Selected Publications / All Publications

Oğuz, Alaattin, ve Sunay Oğuz. “MÜLTECİLERE DÖNÜK NEFRET SÖYLEMİ VE TOPLUMSAL DÜZENSİZLİK”. Pamukkale Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, sy. 56 (Mayıs 2023): 31-42. https://doi.org/10.30794/pausbed.1197380.